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斯洛文尼亚黄囊蛛(Cheiracanthium punctorium)咬伤:病例系列及综述

Yellow sac spider (Cheiracanthium punctorium) bites in Slovenia: case series and review.

作者信息

Varl Tanja, Grenc Damjan, Kostanjšek Rok, Brvar Miran

机构信息

Centre for Clinical Toxicology and Pharmacology, Division of Internal Medicine, University Medical Centre Ljubljana, Zaloška cesta 7, 1000, Ljubljana, Slovenia.

Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000, Ljubljana, Slovenia.

出版信息

Wien Klin Wochenschr. 2017 Sep;129(17-18):630-633. doi: 10.1007/s00508-017-1217-8. Epub 2017 May 24.

DOI:10.1007/s00508-017-1217-8
PMID:28540455
Abstract

In Central Europe, reports of human envenomation by Cheiracanthium punctorium, commonly known as the yellow sac spider, are sporadic, despite the fact that this species is widespread in Europe. However, in recent years, C. punctorium has been repeatedly described globally in medical and toxicological literature. Its venom was found to possess insecticidal, haemolytic, cytotoxic, and membrane-damaging activities. Its bite is often very painful, frequently associated with local and transient cutaneous and neurotoxic effects, but sometimes also with systemic symptoms which require medical help. The main objective of this article is to introduce more details about C. punctorium, the clinical manifestations and circumstances of its bite, the characteristics of its venom and proposed clinical management. The authors provide case reports of patients bitten by C. punctorium during the 10-year observational period. All patients presented in this article showed generally mild clinical manifestations and recovered completely without sequelae. No further treatment in terms of hospital surveillance or specific clinical measures was necessary in any of the reported cases.

摘要

在中欧,尽管黄斑园蛛(俗称黄囊蛛)在欧洲广泛分布,但关于人类被其蜇伤的报告却很零散。然而,近年来,黄斑园蛛在全球医学和毒理学文献中被多次描述。人们发现其毒液具有杀虫、溶血、细胞毒性和膜损伤活性。其叮咬通常非常疼痛,常伴有局部和短暂的皮肤及神经毒性作用,但有时也会出现需要医疗救助的全身症状。本文的主要目的是介绍更多关于黄斑园蛛的细节、其叮咬的临床表现和情况、毒液的特性以及建议的临床处理方法。作者提供了在10年观察期内被黄斑园蛛叮咬患者的病例报告。本文中介绍的所有患者临床表现总体较轻,均完全康复且无后遗症。在所报告的任何病例中,均无需进行进一步的医院监测或采取特定临床措施。

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本文引用的文献

1
Rapid genetic and ecological differentiation during the northern range expansion of the venomous yellow sac spider in Europe.欧洲有毒黄囊蜘蛛在向北范围扩张过程中的快速遗传和生态分化。
Evol Appl. 2016 Aug 17;9(10):1229-1240. doi: 10.1111/eva.12392. eCollection 2016 Dec.
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Araneae Sloveniae: a national spider species checklist.《斯洛文尼亚蜘蛛:国家蜘蛛物种名录》
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Structure of the yellow sac spider Cheiracanthium punctorium genes provides clues to evolution of insecticidal two-domain knottin toxins.
黄囊蛛。
Wien Klin Wochenschr. 2018 Jan;130(1-2):76. doi: 10.1007/s00508-017-1288-6. Epub 2017 Nov 6.
黄斑园蛛(Cheiracanthium punctorium)基因结构为杀虫双结构域结蛋白毒素的进化提供线索。
Insect Mol Biol. 2014 Aug;23(4):527-38. doi: 10.1111/imb.12097. Epub 2014 Apr 10.
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Swiss prospective study on spider bites.瑞士蜘蛛咬伤前瞻性研究。
Swiss Med Wkly. 2013 Sep 4;143:w13877. doi: 10.4414/smw.2013.13877. eCollection 2013.
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A two year study of verified spider bites in Switzerland and a review of the European spider bite literature.一项对瑞士已证实的蜘蛛咬伤的两年研究和对欧洲蜘蛛咬伤文献的回顾。
Toxicon. 2013 Oct;73:104-10. doi: 10.1016/j.toxicon.2013.07.010. Epub 2013 Jul 18.
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An extensive case of dermonecrotic arachnidism.一例广泛的皮肤坏死性蛛形纲动物中毒病例。
J Clin Aesthet Dermatol. 2009 Sep;2(9):40-3.
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J Biol Chem. 2010 Oct 15;285(42):32293-302. doi: 10.1074/jbc.M110.104265. Epub 2010 Jul 24.
8
Verified bites by yellow sac spiders (genus Cheiracanthium) in the United States and Australia: where is the necrosis?在美国和澳大利亚经证实的黄囊蛛(Cheiracanthium属)咬伤病例:坏死在哪里?
Am J Trop Med Hyg. 2006 Jun;74(6):1043-8.
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The global epidemiology, syndromic classification, management, and prevention of spider bites.蜘蛛咬伤的全球流行病学、综合征分类、管理及预防
Am J Trop Med Hyg. 2004 Aug;71(2):239-50.