Han Zhiyong, Elliott Mark S
Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, 20037.
Biochem Mol Biol Educ. 2017 Nov;45(6):469-474. doi: 10.1002/bmb.21069. Epub 2017 May 19.
In the human body, the adrenal steroids collectively regulate a plethora of fundamental functions, including electrolyte and water balance, blood pressure, stress response, intermediary metabolism, inflammation, and immunity. Therefore, adrenal steroidogenesis is an important biochemistry topic for students to learn in order for them to understand health consequences caused by deficiencies of enzymes in the adrenal steroidogenic pathways. However, popular biochemistry textbooks contain insufficient information and may sometimes give students a misimpression about certain aspects of human adrenal steroidogenesis. This article highlights two neglected issues in teaching human adrenal steroidogenesis in popular biochemistry textbooks. The purpose of this article is to draw attention to these issues. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(6):469-474, 2017.
在人体中，肾上腺类固醇共同调节大量基本功能，包括电解质和水平衡、血压、应激反应、中间代谢、炎症和免疫。因此，肾上腺类固醇生成是学生学习的一个重要生物化学课题，以便他们了解肾上腺类固醇生成途径中酶缺乏所导致的健康后果。然而，流行的生物化学教科书包含的信息不足，有时可能会让学生对人类肾上腺类固醇生成的某些方面产生误解。本文强调了在流行的生物化学教科书中教授人类肾上腺类固醇生成时被忽视的两个问题。本文的目的是引起人们对这些问题的关注。© 2017年，国际生物化学与分子生物学联盟，45(6):469 - 474，2017。
