Edwards Christina H, Bekkevold Terese, Flem Elmira
Department of Infectious Disease Epidemiology and Modelling, Norwegian Institute of Public Health, Oslo, Norway.
Department of Vaccine-Preventable Diseases, Norwegian Institute of Public Health, Oslo, Norway.
Vaccine. 2017 Jun 16;35(28):3528-3533. doi: 10.1016/j.vaccine.2017.05.037. Epub 2017 May 22.
Cost-effectiveness of rotavirus vaccination is affected by assumptions used in health economic evaluations. To inform such evaluations, we assessed healthcare use before and after hospitalisations due to rotavirus and other acute gastroenteritis (AGE) among children <5years of age in Norway and estimated daycare and work absenteeism.
We conducted post-discharge interviews with caregivers of 282 children hospitalised with AGE at two hospitals in Norway during April 2014-February 2017. We collected data on healthcare use and absenteeism from daycare and work. We examined healthcare seeking and absenteeism patterns for RV-specific and other gastroenteritis.
Caregivers of 485 (37%) of 1 298 hospitalised children were invited to participate, and 282 (58%) completed the questionnaire. Among these, 106 (38%) were rotavirus-positive, 119 (42%) were rotavirus-negative, and for 57 (20%) children no rotavirus testing was performed. Overall, 97% of children had been in contact with a healthcare provider before hospital admission and 28% had contacted a healthcare provider after discharge. Children that attended daycare were absent from daycare for a mean of 6.3days (median 5days). Caregivers of these children reported work absenteeism in 74% of cases. The mean duration of work absenteeism among caregivers was 5.9days (median 5days) both for RV-positive and RV-negative cases.
In Norway, work absenteeism and healthcare use before and after hospitalisation due to rotavirus and non-rotavirus gastroenteritis are considerable and impose an economic burden on the healthcare system and society.
轮状病毒疫苗接种的成本效益受卫生经济评估中所用假设的影响。为指导此类评估，我们评估了挪威5岁以下儿童因轮状病毒和其他急性胃肠炎（AGE）住院前后的医疗保健使用情况，并估计了日托缺勤和工作缺勤情况。
2014年4月至2017年2月期间，我们对挪威两家医院282名因AGE住院儿童的护理人员进行了出院后访谈。我们收集了日托和工作中医疗保健使用及缺勤的数据。我们研究了轮状病毒特异性和其他胃肠炎的就医及缺勤模式。
1298名住院儿童中的485名（37%）护理人员被邀请参与，282名（58%）完成了问卷。其中，106名（38%）为轮状病毒阳性，119名（42%）为轮状病毒阴性，57名（20%）儿童未进行轮状病毒检测。总体而言，97%的儿童在入院前曾与医疗服务提供者接触，28%的儿童在出院后与医疗服务提供者接触。参加日托的儿童日托缺勤平均为6.3天（中位数5天）。这些儿童的护理人员报告74%的病例有工作缺勤。轮状病毒阳性和轮状病毒阴性病例中，护理人员工作缺勤的平均持续时间均为5.9天（中位数5天）。
在挪威，因轮状病毒和非轮状病毒胃肠炎住院前后的工作缺勤和医疗保健使用情况相当严重，给医疗系统和社会带来了经济负担。
