大量急性砷中毒后无周围神经病变存活：经2,3-二巯基丙烷-1-磺酸盐治疗。
Survival without peripheral neuropathy after massive acute arsenic poisoning: Treated by 2,3-dimercaptopropane-1-sulphonate.
作者信息
Lu P-H, Tseng J-C, Chen C-K, Chen C-H
机构信息
Division of Clinical Pharmacy, Department of Pharmacy, Chang Gung Memorial Hospital, Linkou, Taiwan.
Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.
出版信息
J Clin Pharm Ther. 2017 Aug;42(4):506-508. doi: 10.1111/jcpt.12538. Epub 2017 May 25.
WHAT IS KNOWN AND OBJECTIVE
Massive acute arsenic poisoning is rare yet potentially life-threatening. 2,3-dimercaptopropane-1-sulphonate (DMPS) appears to have the appropriate chelating property. However, clinical experience on the use of DMPS in massive arsenic poisoning is limited.
CASE DESCRIPTION
A 37-year-old woman attempted suicide by ingesting 37.5 g of arsenic trioxide. DMPS was promptly initiated based on history and clinical symptoms. The patient recovered completely, with no complications or side effects of the therapy.
WHAT IS NEW AND CONCLUSION
TDMPS is useful for the treatment of massive acute arsenic poisoning.
已知信息与目的
大规模急性砷中毒虽罕见但可能危及生命。2,3-二巯基丙烷-1-磺酸钠（DMPS）似乎具有合适的螯合特性。然而，DMPS用于大规模砷中毒的临床经验有限。
病例描述
一名37岁女性摄入37.5克三氧化二砷企图自杀。根据病史和临床症状迅速开始使用DMPS治疗。患者完全康复，治疗过程中无并发症或副作用。
新发现与结论
DMPS对大规模急性砷中毒的治疗有效。
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