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儿童长期存在病变引发的原发性皮肤B细胞淋巴母细胞淋巴瘤及文献综述

Primary Cutaneous B-Cell Lymphoblastic Lymphoma Arising from a Long-Standing Lesion in a Child and Review of the Literature.

作者信息

Song Hannah, Todd Patricia, Chiarle Roberto, Billett Amy L, Gellis Stephen

机构信息

Harvard Medical School, Boston, Massachusetts.

Dermatology Program, Boston Children's Hospital, Boston, Massachusetts.

出版信息

Pediatr Dermatol. 2017 Jul;34(4):e182-e186. doi: 10.1111/pde.13169. Epub 2017 May 26.

Abstract

Precursor B-cell lymphoblastic lymphoma (B-LBL) is a rare entity and primary cutaneous B-LBL is an even more uncommon diagnosis that typically affects children. A 4-year-old boy presented with a persistent rash on his left cheek for almost 2 years and was found to have primary cutaneous B-LBL. We report this case to emphasize that B-LBL should be in the differential diagnosis for an otherwise unimpressive persistent lesion in the head and neck region and review all reported pediatric cases of primary cutaneous B-LBL without extracutaneous involvement.

摘要

前体B细胞淋巴母细胞淋巴瘤(B-LBL)是一种罕见的疾病,而原发性皮肤B-LBL的诊断更为罕见,通常影响儿童。一名4岁男孩左侧脸颊出现持续皮疹近2年,被诊断为原发性皮肤B-LBL。我们报告此病例以强调,对于头颈部区域看似不严重的持续性病变,B-LBL应列入鉴别诊断,并回顾所有报道的无皮肤外受累的儿童原发性皮肤B-LBL病例。

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