Song Hannah, Todd Patricia, Chiarle Roberto, Billett Amy L, Gellis Stephen
Harvard Medical School, Boston, Massachusetts.
Dermatology Program, Boston Children's Hospital, Boston, Massachusetts.
Pediatr Dermatol. 2017 Jul;34(4):e182-e186. doi: 10.1111/pde.13169. Epub 2017 May 26.
Precursor B-cell lymphoblastic lymphoma (B-LBL) is a rare entity and primary cutaneous B-LBL is an even more uncommon diagnosis that typically affects children. A 4-year-old boy presented with a persistent rash on his left cheek for almost 2 years and was found to have primary cutaneous B-LBL. We report this case to emphasize that B-LBL should be in the differential diagnosis for an otherwise unimpressive persistent lesion in the head and neck region and review all reported pediatric cases of primary cutaneous B-LBL without extracutaneous involvement.
前体B细胞淋巴母细胞淋巴瘤(B-LBL)是一种罕见的疾病,而原发性皮肤B-LBL的诊断更为罕见,通常影响儿童。一名4岁男孩左侧脸颊出现持续皮疹近2年,被诊断为原发性皮肤B-LBL。我们报告此病例以强调,对于头颈部区域看似不严重的持续性病变,B-LBL应列入鉴别诊断,并回顾所有报道的无皮肤外受累的儿童原发性皮肤B-LBL病例。