• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Accelerating chemical reactions by molecular sledding.

作者信息

Zhang Lei, Zheng Lifei, Meng Zhuojun, Balinin Konstantin, Loznik Mark, Herrmann Andreas

机构信息

Zernike Institute for Advanced Materials, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

出版信息

Chem Commun (Camb). 2017 Jun 8;53(47):6331-6334. doi: 10.1039/c7cc02500a.

DOI:10.1039/c7cc02500a
PMID:28548153
Abstract

The speed-up of covalent bond formation was achieved between a sulfhydryl group and a 2-bromopropionic acid derivative by utilizing sliding peptide-modified substrates. Moreover, a new type of DNA cleaving reagent was developed, consisting of pVIc covalently coupled to verteporfin. This peptide-porphyrin conjugate allowed targeting of DNA and resulted in increased photodegradation of double-stranded nucleic acids.

摘要

相似文献

1
Accelerating chemical reactions by molecular sledding.
Chem Commun (Camb). 2017 Jun 8;53(47):6331-6334. doi: 10.1039/c7cc02500a.
2
In the virion, the 11-amino-acid peptide cofactor pVIc is covalently linked to the adenovirus proteinase.在病毒粒子中，11个氨基酸的肽辅因子pVIc与腺病毒蛋白酶共价连接。
Virology. 2002 May 10;296(2):234-40. doi: 10.1006/viro.2002.1394.
3
Interaction of the adenovirus proteinase with protein cofactors with high negative charge densities.腺病毒蛋白酶与具有高负电荷密度的蛋白质辅因子的相互作用。
Biochemistry. 2005 Jun 21;44(24):8721-9. doi: 10.1021/bi0502240.
4
DNA binding and cleavage by a cationic manganese porphyrin-peptide nucleic acid conjugate.阳离子锰卟啉-肽核酸共轭物的DNA结合与切割
Bioconjug Chem. 1997 May-Jun;8(3):267-70. doi: 10.1021/bc9700190.
5
Versatile phosphoramidation reactions for nucleic acid conjugations with peptides, proteins, chromophores, and biotin derivatives.用于与肽、蛋白质、生色团和生物素衍生物进行核酸缀合的多功能磷酰胺反应。
Bioconjug Chem. 2010 Sep 15;21(9):1642-55. doi: 10.1021/bc1001505.
6
[A new method of covalent immobilization of oligodeoxyribonucleotides on nylon membranes for hybridization with nucleic acids].[一种将寡脱氧核糖核苷酸共价固定在尼龙膜上用于与核酸杂交的新方法]
Mol Biol (Mosk). 1994 Sep-Oct;28(5):1176-82.
7
[Chemical reactions in double-helical nucleic acids. XVI. Synthesis of DNA-duplexes containing regularly repeating transverse covalent cross- links].[双螺旋核酸中的化学反应。十六。含规则重复横向共价交联的DNA双链体的合成]
Bioorg Khim. 1994 Jan;20(1):40-9.
8
Furan-PNA: a mildly inducible irreversible interstrand crosslinking system targeting single and double stranded DNA.呋喃-PNA：一种靶向单链和双链DNA的轻度可诱导不可逆链间交联系统。
Chem Commun (Camb). 2016 May 25;52(42):6930-3. doi: 10.1039/c6cc02062c. Epub 2016 May 5.
9
HIV-1 nucleocapsid protein as a nucleic acid chaperone: spectroscopic study of its helix-destabilizing properties, structural binding specificity, and annealing activity.HIV-1核衣壳蛋白作为核酸伴侣：对其螺旋去稳定特性、结构结合特异性及退火活性的光谱学研究
J Mol Biol. 2002 May 3;318(3):749-64. doi: 10.1016/S0022-2836(02)00043-8.
10
Nuclease activity and binding characteristics of a cationic "manganese porphyrin-bis(benzimidazole) dye (Hoechst 33258)" conjugate.一种阳离子“锰卟啉 - 双（苯并咪唑）染料（Hoechst 33258）”共轭物的核酸酶活性和结合特性
Bioconjug Chem. 1997 Mar-Apr;8(2):222-31. doi: 10.1021/bc970007e.

引用本文的文献

1
Cell-Penetrating Peptides Predicted From CASC3, AKIP1, and AHRR Proteins.从CASC3、AKIP1和AHRR蛋白预测的细胞穿透肽。
Front Pharmacol. 2021 Aug 24;12:716226. doi: 10.3389/fphar.2021.716226. eCollection 2021.
2
Catalytic transport of molecular cargo using diffusive binding along a polymer track.使用聚合物轨道上的扩散结合催化分子货物的运输。
Nat Chem. 2019 Apr;11(4):359-366. doi: 10.1038/s41557-018-0204-7. Epub 2019 Jan 21.
3
A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA.
一种用于研究分子沿DNA转运的简单、稳健且高通量的单分子流拉伸分析方法
J Vis Exp. 2017 Oct 1(128):55923. doi: 10.3791/55923.