Zhu Xiao-Tong, Zhao Qi, Liu Feng, Wang Ai-Fang, Cai Pei-Jun, Hao Wen-Juan, Tu Shu-Jiang, Jiang Bo
School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, 221116, P. R. China.
Chem Commun (Camb). 2017 Jun 22;53(51):6828-6831. doi: 10.1039/c7cc01666b.
A new silver-mediated 5-exo-dig cyclization of 2-alkynylbenzonitriles with disubstituted phosphine oxide and HO has been developed. The reaction enables multiple bond-forming events including C-P, C-C and C-O bonds under atmospheric conditions, leading to the concise and direct formation of 28 examples of phosphorus-containing 1-indenones with generally good yields.
已开发出一种新型银介导的2-炔基苯甲腈与二取代氧化膦及HO的5-外向-环化反应。该反应能够在常压条件下实现包括C-P、C-C和C-O键在内的多个成键过程，从而简洁直接地合成了28个含磷的1-茚酮实例，产率普遍良好。
