Ohya Ayumi, Higuchi Kayoko, Shimojo Hisashi, Fujinaga Yasunari, Kadoya Masumi, Shiohara Shigeki
Department of Radiology, Shinshu University School of Medicine, Matsumoto, Japan.
Department of Surgical Pathology, Aizawa Hospital, Matsumoto, Japan.
J Obstet Gynaecol Res. 2017 Aug;43(8):1360-1365. doi: 10.1111/jog.13353. Epub 2017 May 26.
Herein, we report a rare case of an epithelioid trophoblastic tumor of the uterus with radiologic-pathologic correlation in a 56-year-old postmenopausal woman. On T2-weighted magnetic resonance (MR) imaging, the tumor appeared as a hypointense irregular mass compared with the surrounding myometrium of the uterine corpus and encircled the cavity of the lower uterine segment. On dynamic contrast-enhanced MR images, the tumor appeared as a hypovascular mass and an inhomogeneously hyperintense mass in the delayed phase. In addition, non-contrast computed tomography images showed some spotty areas of very high density within the tumor. These radiologic findings were well correlated with the histological features, such as abundant hyalinization and calcification within the tumor. Accurate interpretation of MR and computed tomography findings was helpful to differentiate epithelioid trophoblastic tumor from other gestational trophoblastic diseases and uterine carcinomas.
在此，我们报告一例罕见的子宫上皮样滋养细胞肿瘤病例，该病例来自一名56岁的绝经后女性，具有放射学与病理学相关性。在T2加权磁共振（MR）成像上，与子宫体周围的肌层相比，肿瘤表现为低信号不规则肿块，并环绕子宫下段的宫腔。在动态对比增强MR图像上，肿瘤在延迟期表现为低血供肿块和不均匀高信号肿块。此外，非增强计算机断层扫描图像显示肿瘤内有一些非常高密度的斑点状区域。这些放射学表现与肿瘤内丰富的玻璃样变和钙化等组织学特征密切相关。准确解读MR和计算机断层扫描结果有助于将上皮样滋养细胞肿瘤与其他妊娠滋养细胞疾病及子宫癌相鉴别。
