氯化腺苷类似物DTA-35对人淋巴细胞环核苷酸磷酸二酯酶的抑制作用。
Inhibition of human lymphocyte cyclic nucleotide phosphodiesterases by the chlorinated adenosine analog DTA-35.
作者信息
Hurwitz M Y, Hurwitz R L, Edstrom R D
机构信息
Department of Biochemistry, University of Minnesota, Minneapolis 55455.
出版信息
J Enzyme Inhib. 1987;1(4):267-74. doi: 10.3109/14756368709020124.
PMID:2854846
Abstract
Human (E+)-T-lymphocytes have multiple cyclic nucleotide phosphodiesterase activities, some of which are markedly inhibited by the chlorinated adenosine derivative 9-(3',5'-dichloro-2',3',5'-trideoxy-beta-D-threo-pentofuranosyl)adenine (DTA-35).
摘要
人（E+）-T淋巴细胞具有多种环核苷酸磷酸二酯酶活性，其中一些活性受到氯化腺苷衍生物9-（3'，5'-二氯-2'，3'，5'-三脱氧-β-D-苏式-戊呋喃糖基）腺嘌呤（DTA-35）的显著抑制。
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