Departments of1Neurology and.
2Neurological Surgery, Columbia University, New York, New York.
J Neurosurg. 2018 Mar;128(3):867-870. doi: 10.3171/2016.12.JNS161727. Epub 2017 May 26.
Electrical stimulation mapping (ESM) is considered the gold standard for identification of essential language cortex and is especially important in patients for whom classic language landmarks are less useful because of reorganization in response to epileptogenic or neoplastic cortex. However, little is known regarding the reliability of the procedure, particularly over extended time intervals. The authors present the case of a young man with refractory left temporal lobe epilepsy in the setting of a low-grade left temporal tumor who had undergone intraoperative language mapping at age 14 years and repeat mapping at age 25. Results from both the initial ESM and the repeat ESM 11 years later revealed a positive auditory description naming site in the same location on the superior temporal gyrus, at the anterior aspect of the tumor. This case provides support for the reliability of ESM and underscores intraindividual reliability in the location of language cortex over a prolonged period.
电刺激定位（ESM）被认为是确定语言皮质的金标准，对于那些由于致痫灶或肿瘤皮质的重组而经典语言标志物不太有用的患者，这一点尤为重要。然而，对于该过程的可靠性，尤其是在较长的时间间隔内，人们知之甚少。作者报告了一例年轻男性，他患有难治性左侧颞叶癫痫，左侧颞部有低级别的肿瘤，他在 14 岁时接受了术中语言定位，在 25 岁时再次接受了定位。初次 ESM 和 11 年后的重复 ESM 的结果均显示，在肿瘤前部的颞上回相同位置有一个阳性的听觉描述命名区。这个病例为 ESM 的可靠性提供了支持，并强调了在较长时间内语言皮质的个体内可靠性。
