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[巴氯芬和蝇蕈醇对鲤鱼中脑顶盖在视觉和躯体感觉传入输入刺激下诱发电位的影响]

[Effect of baclofen and muscimol on the evoked potentials of the tectum mesencephali in the carp in response to stimulation of the visual and somatosensory afferent inputs].

作者信息

Garina N S, Erchenkov V G, Potapov A A

出版信息

Neirofiziologiia. 1988;20(6):809-11.

PMID:2854884
Abstract

The perfusion of (+/-) 10(-5) M baclofen to the optic tectum of the carp greatly reduced evoked potential to the optic nerve stimulation and slightly inhibited evoked potential to the spinal cord stimulation. The perfusion of 10(-4) M muscimol reduced the former evoked potential as well as the latter one. The results permit supposing that tectal visual input is more sensitive to the presynaptic inhibitory influences through GABAB-receptors than the somatosensory afferent input.

摘要

向鲤鱼视顶盖灌注(±)10^(-5)M巴氯芬可大大降低对视神经刺激的诱发电位,并轻微抑制对脊髓刺激的诱发电位。灌注10^(-4)M蝇蕈醇可降低前者以及后者的诱发电位。这些结果表明,顶盖视觉输入比躯体感觉传入输入对通过GABAB受体的突触前抑制影响更敏感。

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