Phosphorylation at Ser as an intrinsic regulatory switch to regulate the morphologies and structures of Alzheimer's 40-residue β-amyloid (Aβ40) fibrils.
作者信息
Hu Zhi-Wen, Ma Meng-Rong, Chen Yong-Xiang, Zhao Yu-Fen, Qiang Wei, Li Yan-Mei
出版信息
J Biol Chem. 2017 May 26;292(21):8846. doi: 10.1074/jbc.A116.757179.
Abstract
摘要
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Phosphorylation at Ser as an intrinsic regulatory switch to regulate the morphologies and structures of Alzheimer's 40-residue β-amyloid (Aβ40) fibrils.丝氨酸磷酸化作为一种内在调节开关，用于调控阿尔茨海默病40个氨基酸残基的β-淀粉样蛋白（Aβ40）纤维的形态和结构。
J Biol Chem. 2017 May 26;292(21):8846. doi: 10.1074/jbc.A116.757179.
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