Wu Jun, Ward Eileen, Threatt Tiffaney, Lu Zhiqiang K
J Am Pharm Assoc (2003). 2017 Jul-Aug;57(4):483-487. doi: 10.1016/j.japh.2017.04.008. Epub 2017 May 24.
To describe prescribing patterns of metformin in low-income and Medicaid-insured patients with prediabetes and to identify common demographic characteristics and comorbid conditions of low-income and Medicaid-insured patients receiving metformin for treatment of prediabetes.
Retrospective observational study.
Patients (18-60 years old) who were enrolled in South Carolina Medicaid and diagnosed with prediabetes between January 2009 and December 2013.
Metformin prescribing to treat prediabetes identified from pharmacy claims.
Among 7102 patients who met the study criteria, 7.4% (n = 520) were prescribed metformin for prediabetes. Nearly 45% (n = 238) of eligible patients prescribed metformin initiated treatment within 30 days after diagnosis of prediabetes. Twenty-five percent of those prescribed metformin took 280 days or longer to initiate treatment after diagnosis of prediabetes. Older age, black race, managed care plan, comorbid hypertension and obesity, and longer enrollment period significantly increased the likelihood of metformin prescribing to treat prediabetes.
Prevalence of metformin prescription to treat prediabetes is less than 8% in low-income and Medicaid-insured patients. Sociodemographic characteristics and comorbid conditions influenced metformin prescribing in the low-income population.
描述二甲双胍在低收入及参加医疗补助计划的糖尿病前期患者中的处方模式,并确定接受二甲双胍治疗糖尿病前期的低收入及参加医疗补助计划患者的常见人口统计学特征和合并症。
回顾性观察研究。
2009年1月至2013年12月期间参加南卡罗来纳州医疗补助计划并被诊断为糖尿病前期的18至60岁患者。
从药房报销记录中确定的用于治疗糖尿病前期的二甲双胍处方。
在符合研究标准的7102名患者中,7.4%(n = 520)被处方使用二甲双胍治疗糖尿病前期。在符合条件并被处方使用二甲双胍的患者中,近45%(n = 238)在糖尿病前期诊断后的30天内开始治疗。在被处方使用二甲双胍的患者中,25%在糖尿病前期诊断后280天或更长时间才开始治疗。年龄较大、黑人种族、管理式医疗计划、合并高血压和肥胖症以及参保时间较长显著增加了使用二甲双胍治疗糖尿病前期的可能性。
在低收入及参加医疗补助计划的患者中,使用二甲双胍治疗糖尿病前期的处方率不到8%。社会人口统计学特征和合并症影响了低收入人群中二甲双胍的处方情况。