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2011-2018 年基层医疗环境中对糖尿病前期患者的治疗:一项观察性研究。

Treatment of Patients with Prediabetes in a Primary Care Setting 2011-2018: an Observational Study.

机构信息

Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

出版信息

J Gen Intern Med. 2021 Apr;36(4):923-929. doi: 10.1007/s11606-020-06354-4. Epub 2021 Jan 15.

Abstract

BACKGROUND

Over one third of American adults are at high risk for developing diabetes, which can be delayed or prevented using interventions such as medical nutrition therapy (MNT) or metformin. Physicians' self-reported rates of prediabetes treatment are improving, but patterns of actual referral, prescription, and MNT visits are unknown.

OBJECTIVE

To characterize treatment of prediabetes in primary care.

DESIGN

We conducted a retrospective cohort study using electronic health record data. We described patterns of treatment and used multivariable logistic regression to evaluate the association of patient factors and PCP-specific treatment rate with patient treatment.

PATIENTS

We included overweight or obese outpatients who had a first prediabetes-range hemoglobin A1c (HbA1c) during 2011-2018 and had primary care provider (PCP) follow-up within a year.

MAIN MEASURES

We collected patient characteristics and the following treatments: metformin prescription; referral to MNT, diabetes education, endocrinology, or bariatric medicine; and MNT visit. We did not capture within-visit physician counseling.

KEY RESULTS

Of 16,713 outpatients with prediabetes, 20.4% received treatment, including metformin prescriptions (7.8%) and MNT referrals (11.3%), but only 7.4% of referred patients completed a MNT visit. The strongest predictor of treatment was the patient's PCP's treatment rate. Some PCPs never treated prediabetes, but two treated more than half of their patients; 62% had no patients complete a MNT visit. Being younger or female and having higher body mass index or HbA1c were also positively associated with treatment. Compared to white patients, black patients were more likely to receive MNT referral and less likely to receive metformin.

CONCLUSIONS

Almost 80% of patients with new prediabetes never received treatment, and those who did receive referrals had very poor visit completion. Treatment rates appear to reflect provider rather than patient preferences.

摘要

背景

超过三分之一的美国成年人有患糖尿病的高风险,通过医学营养疗法(MNT)或二甲双胍等干预措施可以延缓或预防糖尿病的发生。医生报告的糖尿病前期治疗率正在提高,但实际转诊、处方和 MNT 就诊的模式尚不清楚。

目的

描述初级保健中糖尿病前期的治疗情况。

设计

我们使用电子健康记录数据进行了回顾性队列研究。我们描述了治疗模式,并使用多变量逻辑回归评估了患者因素和 PCP 特定治疗率与患者治疗之间的关联。

患者

我们纳入了超重或肥胖的门诊患者,这些患者在 2011-2018 年期间首次出现糖尿病前期范围的糖化血红蛋白(HbA1c),并且在一年内有初级保健提供者(PCP)随访。

主要措施

我们收集了患者特征和以下治疗方法:二甲双胍处方;转介至 MNT、糖尿病教育、内分泌科或减重医学;以及 MNT 就诊。我们没有捕捉到就诊期间医生的咨询。

主要结果

在 16713 名糖尿病前期患者中,有 20.4%接受了治疗,包括二甲双胍处方(7.8%)和 MNT 转诊(11.3%),但只有 7.4%的转诊患者完成了 MNT 就诊。治疗的最强预测因素是患者的 PCP 治疗率。一些 PCP 从未治疗过糖尿病前期,但有两位治疗了超过一半的患者;62%的患者没有完成 MNT 就诊。年轻或女性、更高的体重指数或 HbA1c 与治疗呈正相关。与白人患者相比,黑人患者更有可能接受 MNT 转诊,而接受二甲双胍治疗的可能性较小。

结论

近 80%的新发糖尿病前期患者从未接受过治疗,而那些接受转诊的患者就诊完成率非常低。治疗率似乎反映了提供者而不是患者的偏好。

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