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[年轻癌症患者的生育力保存——我们能否优化路径?]

[FERTILITY PRESERVATION IN YOUNG CANCER PATIENTS - CAN WE OPTIMIZE THE PATH?].

作者信息

Ben-Aharon Irit, Ash Shifra, Ben-Haroush Avi, Perl Gali, Oron Galia, Pinkas Haim, Freud Naphtali, Kravarusic Dragan, Abir Ronit, Sapir Onit, Wiznitzer Arnon, Brenner Baruch, Yaniv Isaac, Stemmer Salomon, Fisch Benjamin

机构信息

Institute of Oncology, Davidoff Center.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv.

出版信息

Harefuah. 2017 May;156(5):326-329.

Abstract

INTRODUCTION

Advances in cancer therapy have improved the long-term survival of cancer patients. Concerns about fertility represent a major issue for young cancer patients. The emergent discipline of oncofertility, an intersection between oncology and fertility, is a new concept that describes an integrated network of clinical resources that focus on fertility preservation from both clinical and research perspectives. Patients and methods: In this article we describe our designated multidisciplinary program for fertility preservation in pediatric and young adult populations. The program is also designed to serve as a prospective platform for the evaluation of reproductive outcomes in this patient cohort.

RESULTS

We have observed considerably higher referral rates following launching the program and earlier referral of chemonaïve patients that concedes maximal fertility preservation. Two hundred and thirty five patients were referred to the program over a period of 3 years.

CONCLUSIONS

Our program demonstrates that multidisciplinary programs that encompass relevant specialists, skilled laboratory resources and a facilitated path that drives the process in the shortest time, maximizes the yield.

摘要

引言

癌症治疗的进展提高了癌症患者的长期生存率。对生育能力的担忧是年轻癌症患者面临的一个主要问题。肿瘤生育学这一新兴学科,是肿瘤学与生育学的交叉领域,是一个新的概念,它描述了一个临床资源整合网络,从临床和研究角度关注生育力保存。

患者与方法

在本文中,我们描述了我们为儿科和年轻成人制定的多学科生育力保存计划。该计划还旨在作为评估该患者群体生殖结局的前瞻性平台。

结果

我们观察到该计划启动后的转诊率显著提高,并且未接受过化疗的患者转诊更早,这有利于最大程度地保存生育力。在3年的时间里,有235名患者被转诊至该计划。

结论

我们的计划表明,多学科计划涵盖相关专家、专业的实验室资源以及在最短时间内推动该过程的便利途径,可使收益最大化。

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