Morgan Michael K
Department of Clinical Medicine, Macquarie University, Sydney, New South Wales, Australia.
Handb Clin Neurol. 2017;143:41-57. doi: 10.1016/B978-0-444-63640-9.00005-9.
Surgical management includes selection of patients for surgery, performing the technical procedure of brain arteriovenous malformation (bAVM) resection and perioperative management that maximize the chance for the best outcome. In general the Spetzler-Ponce class (SPC) can divide patients into those with good evidence that surgery is appropriate in most cases (SPC A), those in whom surgery should only be considered occasionally with highly nuanced indications (SPC C), and surgery may be appropriate having made a detailed analysis of patient (including age), clinical (including mode of presentation), and AVM characteristics (including diffuseness), and a comparative analysis of outcomes with alternate management pathways for SPC B cases. The underlying competent performance of surgery must successfully achieve: consideration of the physiology; correct identification of vessel; protection of the arterial supply to normal brain; understanding of the expected anatomic relationship between feeding arteries and draining veins; and recognition and management of complex arterial feeding patterns from transdural and transosseous sources. Aggressive blood pressure management is required for bAVM with significant changes to brain vascular physiology as a consequence of surgery. For such cases, brain vascular remodeling will take approximately 1 week after surgery. During this period, protection against elevation of blood pressure must be strictly achieved.
手术管理包括为手术选择患者、实施脑动静脉畸形(bAVM)切除的技术操作以及围手术期管理,以最大程度提高获得最佳结果的机会。一般来说,斯佩茨勒-庞塞分级(SPC)可将患者分为以下几类:大多数情况下有充分证据表明手术合适的患者(SPC A);手术仅应在具有高度细微差别的指征时偶尔考虑的患者(SPC C);对于SPC B级病例,在对患者(包括年龄)、临床情况(包括临床表现方式)和AVM特征(包括弥散性)进行详细分析,并与替代管理途径的结果进行比较分析后,手术可能合适的患者。手术的基本胜任能力必须成功实现:考虑生理学因素;正确识别血管;保护正常脑组织的动脉供应;了解供血动脉和引流静脉之间预期的解剖关系;以及识别和处理来自硬膜外和骨内来源的复杂动脉供血模式。由于手术导致脑血管生理学发生重大变化,对于bAVM需要积极进行血压管理。对于此类病例,脑血管重塑在术后大约需要1周时间。在此期间,必须严格防止血压升高。