Lavrent'ev L N
Vopr Onkol. 1979;25(4):38-41.
In chronic strontium-90 administration into rats aged 8--10 months osteosarcomas did not develop, while in animals at the age of 3--4 months osteosarcomas incidence was 6.7%. In single injection of the radionuclide in 8--10 months old animals osteosarcomas developed in 2.2% of observations, whereas in 3--4 months old animals--in 45.7%. The most early appearance of osteosarcomas (at the 193d--316th day) was noted in 3--4 months old animals subjected to a single exposure to strontium-90.
给8 - 10个月大的大鼠长期注射锶-90未诱发骨肉瘤，而3 - 4个月大的动物骨肉瘤发生率为6.7%。对8 - 10个月大的动物单次注射放射性核素，在2.2%的观察对象中出现了骨肉瘤，而3 - 4个月大的动物中这一比例为45.7%。在单次暴露于锶-90的3 - 4个月大的动物中，最早在第193天至316天出现了骨肉瘤。
