Kaimura Michiko, Oda Masako, Mitsubuchi Hiroshi, Ohba Takashi, Katoh Takahiko
Kumamoto University Regional Center, The Japan Environment and Children's Study (JECS).
Department of Neonatology, Kumamoto University Hospital.
Nihon Eiseigaku Zasshi. 2017;72(2):128-134. doi: 10.1265/jjh.72.128.
The purpose of this study was to identify participant characteristics in the Kumamoto University Regional Center of the Japan Environment and Children's Study (K-JECS) and to investigate the association of pregnancy outcomes with pregestational maternal body mass index (BMI) and maternal weight gain during pregnancy (MWG).
The subjects were women with singleton birth, who had been recruited by the K-JECS, and were registered in the data systems for the first and second questionnaires and transcripts of medical records. The subjects were categorized by BMI with further classification by MWG. The chi-squared test and one-way analysis of variance were performed to determine the correlations of BMI and MWG with perinatal outcomes. Logistic regression analysis was performed to examine perinatal outcome risks.
The subject characteristics were similar to the trends observed in the Japanese general population. The odds ratio for natural delivery was low in the overweight groups (OW) and normal weight groups (NW) with excessive weight gain. On the other hand, the risk of cesarean section was high in the OW, and risk of induced or accelerated delivery was high in the NW with excessive weight gain. The risks of preterm birth and LBW were high in the insufficient weight gain groups regardless of BMI. The risks of pregnancy-induced hypertension and gestational diabetes were high in the OW.
本研究旨在确定日本环境与儿童研究熊本大学区域中心(K-JECS)参与者的特征,并调查妊娠结局与孕前母体体重指数(BMI)及孕期体重增加(MWG)之间的关联。
研究对象为K-JECS招募的单胎分娩女性,她们已登记在首次和第二次问卷调查及病历记录的数据系统中。根据BMI对研究对象进行分类,并进一步按MWG进行细分。采用卡方检验和单因素方差分析来确定BMI和MWG与围产期结局的相关性。进行逻辑回归分析以检验围产期结局风险。
研究对象的特征与日本普通人群的趋势相似。超重组(OW)和体重正常组(NW)中体重过度增加者自然分娩的优势比低。另一方面,OW组剖宫产风险高,NW组中体重过度增加者引产或加速分娩风险高。无论BMI如何,体重增加不足组早产和低出生体重风险高。OW组妊娠高血压和妊娠期糖尿病风险高。