Luo Ruixue, Xu Lei, Zhao Weihua, Ma Xiaole, Xu Xiaolei, Kou Juan, Gao Zhao, Becker Benjamin, Kendrick Keith M
Key Laboratory for Neuroinformation, School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.
Key Laboratory for Neuroinformation, School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China.
Psychoneuroendocrinology. 2017 Sep;83:1-8. doi: 10.1016/j.psyneuen.2017.05.020. Epub 2017 May 23.
The neuropeptide oxytocin may increase social cohesion by making us more willing to trust others and/or to conform to their opinions. Here we investigated whether intranasal oxytocin can influence acceptance of advice given on solving everyday social problems by either individual expert (psychologist) or non-expert advisors with or without influencing their perceived likeability or trustworthiness. In a double-blind, between-subject, placebo-control design study in 160 male and female subjects, intranasal oxytocin (24IU) only significantly enhanced acceptance of advice given by female psychologists who were rated as the most trustworthy advisors. However, oxytocin itself did not alter either trustworthiness or likeability ratings. The oxytocin effect on acceptance of the female psychologist's advice was not maintained after a week, with subjects mainly reverting to their original solutions. These findings suggest that while oxytocin can transiently increase acceptance of advice from the most trustworthy individuals this is because it makes subjects more likely to conform to their opinions rather than enhancing their perceived trustworthiness or likeability. Thus in every day contexts oxytocin may primarily promote social cohesion by facilitating conformity towards the opinions of the most trusted individuals.
神经肽催产素可能通过让我们更愿意信任他人和/或认同他人的观点来增强社会凝聚力。在此，我们研究了经鼻给予催产素是否会影响个体专家（心理学家）或非专家顾问就解决日常社会问题给出的建议的接受度，以及这一过程是否会影响对他们的好感度或可信度的感知。在一项针对160名男性和女性受试者的双盲、组间、安慰剂对照设计研究中，经鼻给予催产素（24国际单位）仅显著提高了被评为最值得信赖的顾问的女性心理学家所给出建议的接受度。然而，催产素本身并未改变可信度或好感度评分。一周后，催产素对接受女性心理学家建议的影响不再持续，受试者主要恢复到他们原来的解决方案。这些发现表明，虽然催产素可以暂时提高对最值得信赖的人所提建议的接受度，但这是因为它使受试者更有可能认同他们的观点，而不是提高他们对其可信度或好感度的感知。因此，在日常情境中，催产素可能主要通过促进对最受信任的人的观点的认同来增强社会凝聚力。
