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门静脉肠系膜静脉血栓形成并发失血性休克:腹腔镜胃切除术的一种罕见并发症。

Portomesenteric venous thrombosis complicated by a haemorrhagic shock: a rare complication of laparoscopic gastrectomy.

作者信息

Copelin Eddie, Cholankeril Rosann, Somasundar Ponnandai, Cholankeril George

机构信息

Department of Internal Medicine, Roger Williams Medical Center, Providence, Rhode Island, USA.

Department of Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.

出版信息

BMJ Case Rep. 2017 May 29;2017:bcr-2016-219167. doi: 10.1136/bcr-2016-219167.

DOI:10.1136/bcr-2016-219167
PMID:28554887
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5747676/
Abstract

Portomesenteric venous thrombosis is a rare complication reported in only a few cases involving laparoscopic bariatric surgery. We report a case of a 44-year-old woman who presented 14 days after recent laparoscopic sleeve gastrectomy with the chief complaint of abdominal pain and associated nausea. Abdominal CT demonstrated thrombi in her superior mesenteric, portal and splenic veins. She was initiated on therapeutic heparin but developed haemorrhagic shock shortly afterwards. Subsequent CT angiogram failed to localise the source of her haemorrhage. Her haemodynamic instability improved following a 6-day intensive care unit stay requiring vasopressive agents and blood transfusions. Further hypercoagulable workup revealed that she was a heterozygous carrier of the prothrombin gene mutation, and thus started on lifelong oral anticoagulation.

摘要

门静脉肠系膜静脉血栓形成是一种罕见的并发症,仅在少数涉及腹腔镜减肥手术的病例中有所报道。我们报告一例44岁女性病例,该患者在近期接受腹腔镜袖状胃切除术后14天出现腹痛并伴有恶心的主要症状。腹部CT显示其肠系膜上静脉、门静脉和脾静脉内有血栓形成。她开始接受肝素治疗,但随后不久出现失血性休克。随后的CT血管造影未能确定其出血来源。在重症监护病房住院6天,期间需要使用血管活性药物并输血,之后她的血流动力学不稳定状况有所改善。进一步的高凝状态检查显示她是凝血酶原基因突变的杂合子携带者,因此开始接受终身口服抗凝治疗。

相似文献

1
Portomesenteric venous thrombosis complicated by a haemorrhagic shock: a rare complication of laparoscopic gastrectomy.门静脉肠系膜静脉血栓形成并发失血性休克:腹腔镜胃切除术的一种罕见并发症。
BMJ Case Rep. 2017 May 29;2017:bcr-2016-219167. doi: 10.1136/bcr-2016-219167.
2
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Surg Obes Relat Dis. 2018 Apr;14(4):478-483. doi: 10.1016/j.soard.2017.10.013. Epub 2017 Oct 26.
3
Portomesenteric vein thrombosis after laparoscopic sleeve gastrectomy.腹腔镜袖状胃切除术后肠系膜静脉血栓形成。
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本文引用的文献

1
Portomesenteric Vein Thrombosis After Laparoscopic Sleeve Gastrectomy: 3 Case Reports and a Literature Review.腹腔镜袖状胃切除术后门静脉肠系膜静脉血栓形成:3例报告及文献复习
Am J Case Rep. 2016 Apr 12;17:241-7. doi: 10.12659/ajcr.896892.
2
Portal Vein Thrombosis due to Prothrombin Gene Mutation following Sleeve Gastrectomy.袖状胃切除术后因凝血酶原基因突变导致的门静脉血栓形成
Case Rep Gastrointest Med. 2015;2015:816914. doi: 10.1155/2015/816914. Epub 2015 Nov 10.
3
Portomesenteric venous thrombosis after laparoscopic sleeve gastrectomy: A case report and a call for prevention.腹腔镜袖状胃切除术后门静脉肠系膜静脉血栓形成:一例报告及预防呼吁
J Minim Access Surg. 2015 Oct-Dec;11(4):276-8. doi: 10.4103/0972-9941.152101.
4
Portomesenteric vein thrombosis after laparoscopic sleeve gastrectomy.腹腔镜袖状胃切除术后肠系膜静脉血栓形成。
Surg Endosc. 2014 Apr;28(4):1083-9. doi: 10.1007/s00464-013-3055-8. Epub 2014 Feb 26.
5
Portomesenteric thrombosis following laparoscopic bariatric surgery: incidence, patterns of clinical presentation, and etiology in a bariatric patient population.腹腔镜减重手术后肠系膜静脉血栓形成:在减重患者人群中的发生率、临床表现类型和病因。
JAMA Surg. 2013 Apr;148(4):340-6. doi: 10.1001/jamasurg.2013.1053.
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Portal vein thrombosis following laparoscopic sleeve gastrectomy for morbid obesity.病态肥胖患者腹腔镜袖状胃切除术后门静脉血栓形成
JSLS. 2012 Oct-Dec;16(4):639-43. doi: 10.4293/108680812X13517013316636.
7
Management of portal vein thrombosis.门静脉血栓形成的管理
Gastroenterol Hepatol (N Y). 2008 Oct;4(10):699-700.
8
The long-term risk of venous thromboembolism following bariatric surgery.减重手术后静脉血栓栓塞的长期风险。
Obes Surg. 2011 Sep;21(9):1371-6. doi: 10.1007/s11695-011-0445-7.
9
Abnormalities of prothrombin: a review of the pathophysiology, diagnosis, and treatment.凝血酶原异常:病理生理学、诊断及治疗综述
Haemophilia. 2008 Nov;14(6):1159-63. doi: 10.1111/j.1365-2516.2008.01832.x.
10
Laparoscopic gastric bypass complicated by portal venous thrombosis and severe neurological complications.腹腔镜胃旁路手术并发门静脉血栓形成及严重神经并发症。
Obes Surg. 2008 Sep;18(9):1203-7. doi: 10.1007/s11695-008-9467-1. Epub 2008 May 6.