Zhang Ruiling, Zhang Ruijie, Zou Shichun, Yang Ying, Li Jun, Wang Yinghui, Yu Kefu, Zhang Gan
Guangxi Laboratory on the Study of Coral Reefs in the South China Sea, Nanning, China.
Coral Reef Research Center of China, Guangxi University, Nanning, China.
Bull Environ Contam Toxicol. 2017 Jul;99(1):46-53. doi: 10.1007/s00128-017-2107-5. Epub 2017 May 29.
The occurrence and distribution of five selected fluoroquinolones (FQs) were studied in the Dongjiang River and the Beijiang River, South China. Ciprofloxacin, norfloxacin and enoxacin, used as human and veterinary medicines, were detected with detection frequencies of 75%-100% and average concentrations of 9.5-18.8 ng L in the two rivers. Meanwhile, enrofloxacin, which is only used as veterinary medicine, was detected at lower levels (2.9-4.0 ng L) than those of ciprofloxacin, norfloxacin and enoxacin. The spatial distribution of the five FQs exhibited a close relationship with the intensity of local human activity. Certain antibiotics were detected in industrial wastewater and domestic sewage at considerably higher concentrations than those measured in the river water, indicating important sources of antibiotic contamination. Finally, an ecological risk assessment based on the calculated risk quotient showed that ciprofloxacin could pose high risk to Microcystis aeruginosa (M. aeruginosa). The two rivers are important sources of drinking water and should arouse the attention of relevant departments. Effective measures must be taken to strengthen the protection of the two rivers.
对中国南方东江和北江中的五种选定氟喹诺酮类药物（FQs）的存在情况和分布进行了研究。环丙沙星、诺氟沙星和依诺沙星作为人用和兽用药物，在两条河流中的检出频率为75%-100%，平均浓度为9.5-18.8纳克/升。同时，仅用作兽用药物的恩诺沙星的检出水平（2.9-4.0纳克/升）低于环丙沙星、诺氟沙星和依诺沙星。这五种氟喹诺酮类药物的空间分布与当地人类活动强度密切相关。在工业废水和生活污水中检测到的某些抗生素浓度明显高于河水中测得的浓度，表明抗生素污染的重要来源。最后，基于计算出的风险商数进行的生态风险评估表明，环丙沙星可能对铜绿微囊藻（M. aeruginosa）构成高风险。这两条河流是重要的饮用水源，应引起相关部门的关注。必须采取有效措施加强对这两条河流的保护。
