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高压氧疗法作为突发性感音神经性听力损失的挽救治疗方法。

Hyperbaric Oxygen Therapy as Salvage Therapy for Sudden Sensorineural Hearing Loss.

作者信息

Ajduk Jakov, Ries Mihael, Trotic Robert, Marinac Ivana, Vlatka Kovacic, Bedekovic Vladimir

机构信息

Department of Ear Nose Throat Head and Neck Surgery, Sestre Milosrdnice University Hospital Centre, Zagreb, Croatia.

出版信息

J Int Adv Otol. 2017 Apr;13(1):61-64. doi: 10.5152/iao.2017.3185.

Abstract

OBJECTIVE

To measure the effect of hyperbaric oxygen (HBO) therapy as salvage therapy after the failure of steroid therapy for sudden sensorineural hearing loss (SSNHL).

MATERIALS AND METHODS

Ninety-three patients with SSNHL were unsuccessfully treated with systemic steroid therapy. Following steroid therapy, 43 patients received additional HBO therapy while 50 did not. Hearing levels at 0.25, 0.5, 1, 2, 4, and 8 kHz before and after therapy were measured.

RESULTS

A significant difference in hearing thresholds after HBO therapy was found at all frequencies in patients with a hearing loss of >61 dB. The group of patients with a hearing threshold of ≤60 dB had a significant improvement only at 250 and 500 Hz, while group of patients without additional therapy control group showed no hearing improvement.

CONCLUSION

Hyperbaric oxygen therapy therapy as salvage therapy for SSNHL showed some benefits in hearing improvement. Better results could be expected in patients with severe hearing loss, while in patients with mild-or-moderate hearing loss, recovery should be expected only at low frequencies.

摘要

目的

评估高压氧(HBO)疗法作为突发性感音神经性听力损失(SSNHL)类固醇治疗失败后的挽救治疗的效果。

材料与方法

93例SSNHL患者接受全身类固醇治疗未成功。类固醇治疗后,43例患者接受了额外的HBO治疗,50例未接受。测量治疗前后0.25、0.5、1、2、4和8kHz的听力水平。

结果

听力损失>61dB的患者在接受HBO治疗后,所有频率的听力阈值均有显著差异。听力阈值≤60dB的患者组仅在250和500Hz时有显著改善,而未接受额外治疗的对照组患者听力无改善。

结论

高压氧疗法作为SSNHL的挽救治疗在听力改善方面显示出一定益处。重度听力损失患者有望获得更好的效果,而轻度或中度听力损失患者仅在低频可预期恢复。

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