Department of Oral and Maxillofacial Surgery, Private Practice Dr. Seiler and colleagues, Filderstadt, Germany.
Department of Oral Surgery, University Medical Centre of the Johannes Gutenberg University of Mainz, Mainz, Germany.
Clin Implant Dent Relat Res. 2017 Aug;19(4):725-732. doi: 10.1111/cid.12500. Epub 2017 May 29.
Neurophysiological changes after oral and maxillofacial surgery remain one of the topics of current research.
This study evaluated if implant placement associated with augmentation procedures increases the possibility of sensory disturbances or result in impaired quality of life during the healing period.
Patients who had obtained an implant placement in the lower jaw in combination with augmentation procedures were examined by implementing a comprehensive Quantitative Sensory Testing (QST) protocol for extra- and intraoral use. As augmentation procedures, we used Guided Bone Regeneration (Group A) and Customized Bone Regeneration (Group B) techniques. Patients were tested bilaterally at the chin and mucosal lower lip. Results were compared to a group without augmentation procedures (Group C). Patients' quality of life and psychological comorbidity after the surgical procedures was assessed with the Oral Health Impact Profile and the Hospital Anxiety and Depression Scale.
For groups A (n = 20) and B (n = 8), mechanical QST parameters showed no significant differences in all qualities of the inferior alveolar nerve compared to the contralateral side and compared to the nonaugmentation control group (n = 32) as well. Evaluation of quality of life and psychological factors showed no statistical differences.
Augmentation procedures did not increase sensory disturbances, indicating no changes in the neurophysiological pathways. Extended augmentation procedures did not lead to sensory changes either or result in an impaired quality of life or modified anxiety and depression scores.
口腔颌面手术后的神经生理变化仍然是当前研究的课题之一。
本研究评估了种植体植入联合增强程序是否会增加感觉障碍的可能性，或在愈合期导致生活质量受损。
对接受下颌植入物联合增强程序的患者进行了全面的定量感觉测试（QST）检查，包括口腔内外使用。增强程序分别采用引导骨再生（A 组）和定制骨再生（B 组）技术。对颏部和黏膜下唇双侧进行测试。结果与无增强程序的组（C 组）进行比较。术后患者的生活质量和心理共病采用口腔健康影响量表和医院焦虑抑郁量表进行评估。
A 组（n=20）和 B 组（n=8）的机械 QST 参数在所有下颌神经的质量方面与对侧和非增强对照组（n=32）相比均无显著差异。生活质量和心理因素的评估无统计学差异。
增强程序并未增加感觉障碍，表明神经生理通路没有变化。扩展的增强程序也没有导致感觉变化，或导致生活质量受损或焦虑和抑郁评分改变。
