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口腔面部区域的体感和味觉分析

Somatosensory and Gustatory Profiling in the Orofacial Region.

作者信息

Hartmann Amely, Welte-Jzyk Claudia, Schmidtmann Irene, Geber Christian, Al-Nawas Bilal, Daubländer Monika

机构信息

Private Practice for Oral and Maxillofacial Surgery, Echterdinger Straße 7, 70794 Filderstadt, Germany.

Department of Oral and Maxillofacial Surgery, University Medical Centre of the Johannes Gutenberg University of Mainz, 55131 Mainz, Germany.

出版信息

Diagnostics (Basel). 2022 Dec 16;12(12):3198. doi: 10.3390/diagnostics12123198.

DOI:10.3390/diagnostics12123198
PMID:36553205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9777464/
Abstract

Quantitative sensory testing (QST) is a standard procedure in medicine to describe sensory patterns in various pathologies. The aim of this prospective clinical study was to define reference values of the trigeminal nerve (V3), including taste qualities, to create a compatibility for sensory loss or gain in pathologies. Fifty-one patients were included, and a standardized testing battery with 11 QST parameters according to the German Research Network on Neuropathic Pain (DFNS) was applied complemented by quantitative gustatory assessments. Significant somatosensory differences were found between the test sites (MDT at the chin, WDT at the lower lip) but no effect was detected for gender, age, and between body types. Taste sensitivity was dependent on concentration, gender (females being more sensitive) and increasing age (for bitter and sour taste). We provide reference values for somatosensory and gustatory testing of the facial area. Our data facilitate the detection of neurosensory abnormalities in the orofacial region. This might also serve as a control setting for COVID-19.

摘要

定量感觉测试(QST)是医学中描述各种病理状态下感觉模式的标准程序。这项前瞻性临床研究的目的是确定三叉神经(V3)的参考值,包括味觉特性,以便为病理状态下的感觉丧失或增强建立一种对照标准。纳入了51名患者,并应用了一套根据德国神经性疼痛研究网络(DFNS)制定的包含11个QST参数的标准化测试组合,并辅以定量味觉评估。在测试部位(下巴处的机械性疼痛阈值[MDT]、下唇处的冷痛觉阈值[WDT])之间发现了显著的体感差异,但未检测到性别、年龄和体型之间的影响。味觉敏感性取决于浓度、性别(女性更敏感)和年龄增长(对于苦味和酸味)。我们提供了面部区域体感和味觉测试的参考值。我们的数据有助于检测口面部区域的神经感觉异常。这也可能作为新冠病毒病(COVID-19)的对照标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/f6c1e49379e7/diagnostics-12-03198-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/a36c6e913b1c/diagnostics-12-03198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/f9673a8f1aa6/diagnostics-12-03198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/81cb446eff49/diagnostics-12-03198-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/f6c1e49379e7/diagnostics-12-03198-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/a36c6e913b1c/diagnostics-12-03198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/f9673a8f1aa6/diagnostics-12-03198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/81cb446eff49/diagnostics-12-03198-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/9777464/f6c1e49379e7/diagnostics-12-03198-g004.jpg

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本文引用的文献

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Pain in midlife women: a growing problem in need of further research.中年女性的疼痛:一个亟待进一步研究的日益严重的问题。
Womens Midlife Health. 2022 May 5;8(1):4. doi: 10.1186/s40695-022-00074-x.
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Diagnosis and Management of Lumbar Spinal Stenosis: A Review.腰椎管狭窄症的诊断与治疗:综述
JAMA. 2022 May 3;327(17):1688-1699. doi: 10.1001/jama.2022.5921.
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The evolution of sour taste.酸味的进化。
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Neck pain: global epidemiology, trends and risk factors.颈部疼痛:全球流行病学、趋势和风险因素。
BMC Musculoskelet Disord. 2022 Jan 3;23(1):26. doi: 10.1186/s12891-021-04957-4.
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Sugars and Sweet Taste: Addictive or Rewarding?糖与甜味:使人上瘾还是令人愉悦?
Int J Environ Res Public Health. 2021 Sep 17;18(18):9791. doi: 10.3390/ijerph18189791.
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Orofacial quantitative sensory testing: Current evidence and future perspectives.口腔面感觉定量测试:当前证据和未来展望。
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Quantitative sensory testing of the equine face.马面部的定量感觉测试。
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Anatomy and development of the human taste system.人类味觉系统的解剖结构与发育
Handb Clin Neurol. 2019;164:147-171. doi: 10.1016/B978-0-444-63855-7.00010-1.
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Pain. 2019 May;160 Suppl 1:S66-S69. doi: 10.1097/j.pain.0000000000001544.
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Quantitative sensory testing (QST) in the orofacial region of healthy Chinese: influence of site, gender and age.健康中国人口腔面部区域的定量感觉测试(QST):部位、性别和年龄的影响。
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