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线性釉质发育不全研究中对感兴趣现象的保守评分与排除

Conservative scoring and exclusion of the phenomenon of interest in linear enamel hypoplasia studies.

作者信息

Berti P R, Mahaney M C

机构信息

School of Human Biology, University of Guelph, Guelph, Ontario, Canada NIG 2WI.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78228-0147.

出版信息

Am J Hum Biol. 1995;7(3):313-320. doi: 10.1002/ajhb.1310070307.

DOI:10.1002/ajhb.1310070307
PMID:28557035
Abstract

Conservative criteria are generally employed to select only "sufficiently large" linear enamel defects to be scored as linear enamel hypopasias (LEHs), a practice that excludes enamel defects below arbitrarily selected size thresholds. A question arising is, are such practices likely to exclude small, yet authentic(i.e., physiological stress induced) LEH? The permanent maxillary and mandibular first and second incisors, canines, and first premolars on dental casts (n = 532) form a contemporary Canadian farming commune were scored for LEH, with linear defects being categorized by both breadth and width to yeild the scores A (smallest), B, C, and D (largest). Relative frequencies were calculated as the percent prevalence of each score per tooth divided by the highest percent prevalence exhibited by any tooth in the same dental arch. The intertooth patters of the relative frequencies were tested for concordance. Secondly, assuming that different researchers employ different scoring criteria, tests for concordance of mean n of LEHs/tooth were conducted using data from four different reports as a second test for intertooth concordance of various-sized defects. Substantial concordance was obseved between A, B, C, and D (Kandall's coefficient of concordance, W = .65, P <.005) and in the interstudy comparison (W = .67, P <.01). Because it is unlikely that defects of varying sizes would have similar intertooth distributions if they did not have similar etiologies, it may be inferred that all of the defects observed, even the very small defects, A, are variants of the same phenomenon, LEH. © 1995 Wiley-Liss, Inc.

摘要

通常采用保守标准,仅选择“足够大”的线性釉质缺陷作为线性釉质发育不全(LEH)进行评分,这种做法排除了低于任意选定尺寸阈值的釉质缺陷。由此产生的一个问题是,这种做法是否可能排除小的但真实的(即由生理压力引起的)LEH?对来自当代加拿大农业公社的532个牙模上的恒牙上颌和下颌第一、第二切牙、尖牙和第一前磨牙进行LEH评分,线性缺陷根据宽度和广度进行分类,得出分数A(最小)、B、C和D(最大)。相对频率计算为每颗牙齿各分数的患病率百分比除以同一牙弓中任何牙齿表现出的最高患病率百分比。对相对频率的牙间模式进行一致性检验。其次,假设不同的研究人员采用不同的评分标准,使用来自四份不同报告的数据对每颗牙齿LEH的平均数量的一致性进行检验,作为对各种大小缺陷牙间一致性的第二次检验。在A、B、C和D之间观察到显著的一致性(肯德尔一致性系数,W = 0.65,P < 0.005),在研究间比较中也是如此(W = 0.67,P < 0.01)。如果不同大小的缺陷没有相似的病因,它们不太可能具有相似的牙间分布,因此可以推断,观察到的所有缺陷,即使是非常小的缺陷A,都是同一现象LEH的变体。© 1995威利 - 利斯公司。

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