Resident Physician, Department of Obstetrics and Gynecology.
Clinical Fellow.
Obstet Gynecol Surv. 2017 May;72(5):289-295. doi: 10.1097/OGX.0000000000000425.
Endometrial cancer (EMCA) is the most common gynecologic malignancy, with an estimated 54,000 new cases and 10,000 deaths in the United States in 2015. Lymph node metastasis is the most significant prognostic factor in EMCA. Sentinel lymph node (SLN) mapping has become a well-accepted procedure in surgical oncology and may strike a balance between the risks and benefits of lymphadenectomy.
The aim of this study was to review the current literature regarding the history, techniques, and clinical application of SLN mapping in EMCA.
Evidence was obtained through systematic literature review through PubMed and ClinicalTrials.gov.
Sentinel lymph node biopsy for EMCA is an accepted approach to the staging of this cancer; however, a consensus approach to the SLN biopsy technique and pathologic assessment is needed. Surgeons newly adopting the technique should proceed with caution and care to monitor outcomes.
子宫内膜癌（EMCA）是最常见的妇科恶性肿瘤，据估计 2015 年在美国有 54000 例新发病例和 10000 例死亡病例。淋巴结转移是 EMCA 中最重要的预后因素。前哨淋巴结（SLN）绘图已成为肿瘤外科中一种公认的程序，它可能在淋巴结清扫的风险和益处之间取得平衡。
本研究旨在回顾 SLN 绘图在 EMCA 中的历史、技术和临床应用的现有文献。
通过 PubMed 和 ClinicalTrials.gov 进行系统文献回顾获得证据。
对于 EMCA 前哨淋巴结活检是对这种癌症进行分期的一种可接受的方法；然而，需要对 SLN 活检技术和病理评估达成共识方法。新采用该技术的外科医生应谨慎和小心地进行操作，以监测结果。
