Elborgy Ebrahim, Pulido Jose S
Research Institute of Ophthalmology, Giza, Egypt.
Department of Ophthalmology, Mayo Clinic, Rochester, MN.
Asia Pac J Ophthalmol (Phila). 2017 May-Jun;6(3):256-260. doi: 10.22608/APO.2016205.
To report the occurrence of fibrovascular proliferation (FVP) in the retina in von Hippel-lindau (VHl) patients and its association with prior treatment.
A retrospective study.
A retrospective study of 101 VHL patients. Fundus photos were available for 28 patients. FVP was classified into peripheral and posterior pole.
All 28 patients had retinal capillary hemangioblastomas (RCH) in 1 or both eyes; 15 patients were found to have FVP (group A), whereas 13 patients did not (group B). Mean age of patients in group A was 35 ± 11.3 years and 36.6 ± 13.8 in group B (P = 0.74). In group A, 27 eyes had RCH; 21 (77.77%) had FVP. In group B, 19 eyes had RCH. The number of treated eyes was significantly higher in group A (81.48%) than group B (42.1%) (P = 0.007). In group A, FVP was noted in the posterior pole in 9 eyes, in the periphery in 5 eyes, and 7 eyes developed both posterior pole and peripheral FVP.
FVP can occur in the peripheral retina and in the posterior pole. There is a significant association between prior treatment of RCH and the occurrence of FVP.
报告冯·希佩尔-林道（VHL）病患者视网膜中纤维血管增殖（FVP）的发生情况及其与既往治疗的关联。
一项回顾性研究。
对101例VHL患者进行回顾性研究。28例患者有眼底照片。FVP分为周边部和后极部。
所有28例患者单眼或双眼均有视网膜毛细血管瘤（RCH）；15例患者发现有FVP（A组），而13例患者没有（B组）。A组患者的平均年龄为35±11.3岁，B组为36.6±13.8岁（P = 0.74）。A组中，27只眼有RCH；21只眼（77.77%）有FVP。B组中，19只眼有RCH。A组接受治疗的眼数（81.48%）显著高于B组（42.1%）（P = 0.007）。A组中，9只眼后极部出现FVP，5只眼周边部出现FVP，7只眼后极部和周边部均出现FVP。
FVP可发生于周边视网膜和后极部。RCH的既往治疗与FVP的发生之间存在显著关联。
