Zheng Cheng, Li Jin, Li Jia, Zhou De-Pu, Li Xiao-Wei, Wu Shu-Jie, Lin Jia-Feng
Department of Cardiology, Second Affiliated Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang, 325000, China.
BMC Cardiovasc Disord. 2017 May 30;17(1):140. doi: 10.1186/s12872-017-0575-5.
Ventricular arrhythmias (VAs) originating from the left ventricular summit is a challenge for radiofrequency catheter ablation (RFCA). The present study aimed to investigate the appropriate RFCA strategy for VAs originating from the left ventricular summit.
Forty-five consecutive patients with VAs arising from the left ventricular summit were successfully ablated at our cardiac electrophysiology center and reviewed in the study.
Thirty-two cases of VAs were eliminated in the left ventricular endocardium by retrograde transaortic (n = 22, 22/45, 48.9%) or antegrade transseptal (n = 10, 10/45, 22.2%) approaches, the other 13 cases were eliminated in the left ventricular epicardium by distal great cardiac vein (DGCV) approach (n = 13, 13/45, 28.9%). Though these VAs were similar in electrocardiographic (ECG) morphology, the pseudo delta waves (PDW), intrinsicoid deflection time (IDT), maximal deflection index (MDI) differed among them, PDW >53 ms, IDT > 74 ms, MDI > 0.45 strongly indicated that ablating left ventricular summit VAs by DGCV approach. During mean follow-up of 19.5 ± 13.2 (range, 3-60) months, 2 (4.4%) patients experienced VAs recurrence.
This retrospective study showed that VAs of left ventricular summit origin can be effectively cured with RFCA. For these VAs, prolonged PdW, IDT, MDI indicating RFCA by DGCV approach can be attempted firstly.
起源于左心室嵴的室性心律失常(VAs)是射频导管消融(RFCA)的一项挑战。本研究旨在探讨针对起源于左心室嵴的室性心律失常的合适RFCA策略。
45例连续的起源于左心室嵴的室性心律失常患者在我们的心电生理中心成功接受了消融,并纳入本研究进行回顾分析。
32例室性心律失常通过逆行经主动脉(n = 22,22/45,48.9%)或顺行经房间隔(n = 10,10/45,22.2%)途径在左心室内膜被消除,另外13例通过心大静脉远端(DGCV)途径在左心室心外膜被消除(n = 13,13/45,28.9%)。尽管这些室性心律失常在心电图(ECG)形态上相似,但它们之间的伪δ波(PDW)、类本位曲折时间(IDT)、最大偏转指数(MDI)有所不同,PDW > 53 ms、IDT > 74 ms、MDI > 0.45强烈提示通过DGCV途径消融左心室嵴室性心律失常。在平均19.5 ± 13.2(范围3 - 60)个月的随访期间,2例(4.4%)患者出现室性心律失常复发。
这项回顾性研究表明,起源于左心室嵴的室性心律失常可通过RFCA有效治愈。对于这些室性心律失常,提示通过DGCV途径进行RFCA的延长的PdW、IDT、MDI可首先尝试。