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Sensitive Detection of a Small Parathyroid Adenoma Using Fluorocholine PET/CT: A Case Report.使用氟代胆碱PET/CT对小甲状旁腺腺瘤的灵敏检测：一例报告
Nucl Med Mol Imaging. 2017 Jun;51(2):186-189. doi: 10.1007/s13139-016-0450-9. Epub 2016 Sep 20.
2
A Pilot Comparison of 18F-fluorocholine PET/CT, Ultrasonography and 123I/99mTc-sestaMIBI Dual-Phase Dual-Isotope Scintigraphy in the Preoperative Localization of Hyperfunctioning Parathyroid Glands in Primary or Secondary Hyperparathyroidism: Influence of Thyroid Anomalies.18F-氟胆碱PET/CT、超声检查及123I/99mTc-甲氧基异丁基异腈双相双同位素闪烁扫描术在原发性或继发性甲状旁腺功能亢进症中功能亢进甲状旁腺术前定位的初步比较：甲状腺异常的影响
Medicine (Baltimore). 2015 Oct;94(41):e1701. doi: 10.1097/MD.0000000000001701.
3
Diagnostic Performance of Cervical Ultrasound, Tc-Sestamibi Scintigraphy, and Contrast-Enhanced F-Fluorocholine PET in Primary Hyperparathyroidism.原发性甲状旁腺功能亢进症中颈超声、Tc-Sestamibi 闪烁扫描及 F-Fluorocholine PET 对比增强的诊断性能。
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Comparative Effectiveness of Ultrasonography, 99mTc-Sestamibi, and 18F-Fluorocholine PET/CT in Detecting Parathyroid Adenomas in Patients With Primary Hyperparathyroidism.超声、99mTc-甲氧基异丁基异腈和 18F-氟代胆碱 PET/CT 在原发性甲状旁腺功能亢进症患者甲状旁腺瘤检测中的比较效果。
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Performance of F-18 Fluorocholine PET/CT for Detection of Hyperfunctioning Parathyroid Tissue in Patients with Elevated Parathyroid Hormone Levels and Negative or Discrepant Results in conventional Imaging.氟代胆碱 F-18 PET/CT 对甲状旁腺激素水平升高且常规影像学检查阴性或结果不一致的患者异位甲状旁腺组织的探测效能。
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Comparison of [F]fluorocholine PET/CT with [mTc]sestamibi and ultrasonography to detect parathyroid lesions in primary hyperparathyroidism: a prospective study.[F]氟胆碱PET/CT与[mTc]司他米比及超声检查在原发性甲状旁腺功能亢进症中检测甲状旁腺病变的比较：一项前瞻性研究。
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Preoperative F-18 fluorocholine PET/CT for the detection of hyperfunctioning parathyroid glands in patients with secondary or tertiary hyperparathyroidism: comparison with Tc-99m sestamibi scan and neck ultrasound.术前 F-18 氟胆碱 PET/CT 检测继发性或三发性甲状旁腺功能亢进症患者的高功能甲状旁腺：与 Tc-99m sestamibi 扫描和颈部超声的比较。
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Odd Sites of Parathyroid Adenomas: 18F-fluorocholine PET/CT Pointing to the Right Place.甲状旁腺腺瘤的罕见部位：18F-氟胆碱PET/CT指向正确位置。
Indian J Nucl Med. 2024 Mar-Apr;39(2):123-125. doi: 10.4103/ijnm.ijnm_13_23. Epub 2024 May 29.

引用本文的文献

1
Odd Sites of Parathyroid Adenomas: 18F-fluorocholine PET/CT Pointing to the Right Place.甲状旁腺腺瘤的罕见部位：18F-氟胆碱PET/CT指向正确位置。
Indian J Nucl Med. 2024 Mar-Apr;39(2):123-125. doi: 10.4103/ijnm.ijnm_13_23. Epub 2024 May 29.
2
An anatomic aberration and a surgical challenge: Mediastinal parathyroid adenoma anterior the pericardium. A case report.一种解剖变异与手术挑战：心包前方纵隔甲状旁腺腺瘤。病例报告。
Int J Surg Case Rep. 2019;58:153-156. doi: 10.1016/j.ijscr.2019.04.005. Epub 2019 Apr 6.
3
WITHDRAWN: An anatomic aberration and a surgical challenge: Mediastinal parathyroid adenoma anterior the pericardium. A case report.撤回：一种解剖学异常及手术挑战：心包前方的纵隔甲状旁腺腺瘤。病例报告。
Int J Surg Case Rep. 2019;57:106-109. doi: 10.1016/j.ijscr.2019.03.014. Epub 2019 Mar 21.

本文引用的文献

1
A Pilot Comparison of 18F-fluorocholine PET/CT, Ultrasonography and 123I/99mTc-sestaMIBI Dual-Phase Dual-Isotope Scintigraphy in the Preoperative Localization of Hyperfunctioning Parathyroid Glands in Primary or Secondary Hyperparathyroidism: Influence of Thyroid Anomalies.18F-氟胆碱PET/CT、超声检查及123I/99mTc-甲氧基异丁基异腈双相双同位素闪烁扫描术在原发性或继发性甲状旁腺功能亢进症中功能亢进甲状旁腺术前定位的初步比较：甲状腺异常的影响
Medicine (Baltimore). 2015 Oct;94(41):e1701. doi: 10.1097/MD.0000000000001701.
2
Localization of parathyroid adenoma by ¹¹C-choline PET/CT: preliminary results.¹¹C-胆碱 PET/CT 定位甲状旁腺腺瘤：初步结果。
Clin Nucl Med. 2014 Dec;39(12):1033-8. doi: 10.1097/RLU.0000000000000607.
3
¹⁸F-Fluorocholine PET/CT for localization of hyperfunctioning parathyroid tissue in primary hyperparathyroidism: a pilot study.¹⁸F-氟胆碱PET/CT用于原发性甲状旁腺功能亢进症中功能亢进甲状旁腺组织的定位：一项初步研究。
Eur J Nucl Med Mol Imaging. 2014 Nov;41(11):2083-9. doi: 10.1007/s00259-014-2837-0. Epub 2014 Jul 26.
4
False-positive result in 18F-fluorocholine PET/CT due to incidental and ectopic parathyroid hyperplasia.18F-氟胆碱 PET/CT 检查出现假阳性结果，原因是偶然发生的异位甲状旁腺增生。
Clin Nucl Med. 2014 Jun;39(6):e328-30. doi: 10.1097/RLU.0b013e3182a77b62.
5
Incidental finding of parathyroid adenoma with 11C-choline PET/CT.发现甲状旁腺腺瘤伴 11C-胆碱 PET/CT 显像。
Clin Nucl Med. 2012 Jun;37(6):593-5. doi: 10.1097/RLU.0b013e31824c5ffc.
6
Diagnostic accuracy of 4D-CT for parathyroid adenomas and hyperplasia.4D-CT 对甲状旁腺瘤和增生的诊断准确性。
AJNR Am J Neuroradiol. 2012 Mar;33(3):429-33. doi: 10.3174/ajnr.A2805. Epub 2011 Dec 1.
7
Clinical role of 99mTcO4/MIBI scan, ultrasound and intra-operative gamma probe in the performance of unilateral and minimally invasive surgery in primary hyperparathyroidism.99mTcO4/甲氧基异丁基异腈扫描、超声及术中γ探测仪在原发性甲状旁腺功能亢进单侧及微创手术中的临床作用
Eur J Nucl Med. 2001 Sep;28(9):1351-9.
8
Comparison of parathyroid imaging with technetium-99m-pertechnetate/sestamibi subtraction, double-phase technetium-99m-sestamibi and technetium-99m-sestamibi SPECT.99m锝-高锝酸盐/甲氧基异丁基异腈减影、双时相99m锝-甲氧基异丁基异腈及99m锝-甲氧基异丁基异腈单光子发射计算机断层扫描甲状旁腺显像的比较
J Nucl Med. 1997 Jun;38(6):834-9.
9
Localization of parathyroid adenomas in patients who have undergone surgery. Part I. Noninvasive imaging methods.接受过手术的甲状旁腺腺瘤患者的定位。第一部分。非侵入性成像方法。
Radiology. 1987 Jan;162(1 Pt 1):133-7. doi: 10.1148/radiology.162.1.3538145.

使用氟代胆碱PET/CT对小甲状旁腺腺瘤的灵敏检测：一例报告

Sensitive Detection of a Small Parathyroid Adenoma Using Fluorocholine PET/CT: A Case Report.

作者信息

Padinhare-Keloth Thanseer N T K, Bhadada Sanjay K, Sood Ashwani, Kumar Rajender, Behera Arunanshu, Radotra Bishan D, Mittal Bhagwant R

机构信息

Department of Nuclear Medicine, PGIMER, Sector-12, Chandigarh, 160012 India.

Department of Endocrinology, PGIMER, Chandigarh, 160012 India.

出版信息

Nucl Med Mol Imaging. 2017 Jun;51(2):186-189. doi: 10.1007/s13139-016-0450-9. Epub 2016 Sep 20.

DOI:10.1007/s13139-016-0450-9
PMID:28559945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5429301/
Abstract

Primary hyperparathyroidism is caused by parathyroid adenoma in the majority of cases and diagnosis is usually made biochemically. Pre-surgical localization of parathyroid adenoma is essential to limit the extent of surgery and avoid missing them at ectopic sites. Anatomical and functional imaging are used for the localization, but may fail to identify the small and ectopic parathyroid adenoma. We present a case of small sized ectopic parathyroid adenoma at unusual location detected by F-18 fluorocholine (FCH) PET/CT, where other imaging modalities failed. The post-operative histopathology confirmed the diagnosis of ectopic parathyroid adenoma.

摘要

大多数情况下，原发性甲状旁腺功能亢进由甲状旁腺腺瘤引起，诊断通常通过生化检查进行。甲状旁腺腺瘤的术前定位对于限制手术范围和避免在异位部位遗漏腺瘤至关重要。解剖学和功能成像用于定位，但可能无法识别小的和异位的甲状旁腺腺瘤。我们报告一例在不寻常位置的小尺寸异位甲状旁腺腺瘤病例，该病例通过F-18氟胆碱（FCH）PET/CT检测到，而其他成像方式均未发现。术后组织病理学证实为异位甲状旁腺腺瘤。