Djurić Biljana, Suzić Slavica, Stojadinović Bojana, Nestorović Zorica, Ivanović Marija, Suzić-Lazić Jelena, Nešić Dejan, Mazić Sanja, Tenne Tamar, Zikich Dragoslav, Žikić Dejan
Department of Medical Physiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Institute of Biophysics, Faculty of Medicine, University of Belgrade, Belgrade, 11000, Serbia.
Biomed Microdevices. 2017 Sep;19(3):48. doi: 10.1007/s10544-017-0196-x.
We present here the improved design and development of optical sensor for non-invasive measurements of arterial blood flow waveform. The sensor is based on a physical principle of reflective photoplethysmography (PPG). As the light source we used serially connected infrared diodes whereas NPN silicon phototransistors were used as light detectors. The electronic components were molded into square package and poured with silicone. Such preparation produced an elastic superficies that allowed excellent attachment of the sensor on the skin's surface. Moreover, a serial connection of infrared diodes and phototransistors completely eliminated signal artifacts caused by minor muscle contractions. The sensor recording performances were examined at the photoplethysmographic sites on three different arteries; the commune carotid, femoral and radial and, on each site the sensor demonstrated remarkable capability to make a consistent, reproducible measurements. Because of the advantageous physical and electrical properties, the new sensor is suitable for various cardiovascular diagnostics procedures, especially when long-term measurements of arterial blood flow waveform are required, for monitoring of different parameters in cardiovascular units and for research.
我们在此展示用于无创测量动脉血流波形的光学传感器的改进设计与开发。该传感器基于反射式光电容积脉搏波描记法（PPG）的物理原理。我们使用串联的红外二极管作为光源，而NPN硅光电晶体管用作光探测器。电子元件被模制成方形封装并灌注硅胶。这样的制备产生了一个弹性表面，使得传感器能够很好地附着在皮肤表面。此外，红外二极管和光电晶体管的串联连接完全消除了由轻微肌肉收缩引起的信号伪影。在三条不同动脉（颈总动脉、股动脉和桡动脉）的光电容积脉搏波描记部位对传感器的记录性能进行了检测，并且在每个部位该传感器都表现出了进行一致、可重复测量的卓越能力。由于其有利的物理和电学特性，这种新型传感器适用于各种心血管诊断程序，特别是在需要长期测量动脉血流波形、监测心血管单元中的不同参数以及用于研究时。
