Smith Cardinale B, Phillips Tanyanika, Smith Thomas J
From the Tisch Cancer Institute, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; CHRISTUS St. Frances Cabrini Hospital, Alexandria, LA; Harry J. Duffey Family Patient and Family Services Program, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutions, Baltimore, MD.
Am Soc Clin Oncol Educ Book. 2017;37:714-723. doi: 10.1200/EDBK_175474.
Palliative care alongside usual oncology care is now recommended by ASCO as the standard of care for any patient with advanced cancer on the basis of multiple randomized trials that show better results with concurrent care than with usual oncology care. Some benefits include better quality of life, better symptom management, reduced anxiety and depression, less caregiver distress, more accordance of care with the wishes of the patient, and less aggressive end-of-life care. Several studies show a survival advantage of several months, and many show considerable cost savings: better care at an affordable cost. However, there are not enough palliative care specialists available, so oncologists must practice exemplary primary palliative care. Protocols used in the clinical trials, similar to those designed for new chemotherapy agents, help oncologists use the TEAM approach of extra time, typically an hour a month spent with the palliative care team; education, especially about prognostic awareness and realistic options, which include formal setting of goals of care and discussion of advance directives; formal assessments for symptoms and for spiritual and psychosocial health; and management by an interdisciplinary team. These are all potentially accomplished by an oncology practice to replicate the services provided by concurrent palliative care.
美国临床肿瘤学会(ASCO)现推荐,在常规肿瘤治疗的基础上提供姑息治疗,作为晚期癌症患者的标准治疗方案。多项随机试验表明,与单纯常规肿瘤治疗相比,同步进行姑息治疗效果更佳。其益处包括提高生活质量、更好地管理症状、减轻焦虑和抑郁、减少照护者的痛苦、使治疗更符合患者意愿以及减少过度积极的临终关怀。多项研究显示,患者的生存期可延长数月,且许多研究表明成本大幅节省:以可承受的成本提供更好的治疗。然而,目前姑息治疗专家数量不足,因此肿瘤学家必须提供堪称典范的初级姑息治疗。临床试验中使用的方案,类似于为新型化疗药物设计的方案,有助于肿瘤学家采用TEAM方法,即额外投入时间,通常每月与姑息治疗团队共度一小时;开展教育,尤其是关于预后认知和现实选择的教育,包括正式设定治疗目标和讨论预立医嘱;对症状以及精神和心理社会健康状况进行正式评估;由多学科团队进行管理。肿瘤学实践有可能通过以上方式来复制同步姑息治疗所提供的服务。