McGill University, Montreal, Canada.
American Society of Clinical Oncology (ASCO), Alexandria, VA.
J Clin Oncol. 2024 Jul 1;42(19):2336-2357. doi: 10.1200/JCO.24.00542. Epub 2024 May 15.
To provide evidence-based guidance to oncology clinicians, patients, nonprofessional caregivers, and palliative care clinicians to update the 2016 ASCO guideline on the integration of palliative care into standard oncology for all patients diagnosed with cancer.
ASCO convened an Expert Panel of medical, radiation, hematology-oncology, oncology nursing, palliative care, social work, ethics, advocacy, and psycho-oncology experts. The Panel conducted a literature search, including systematic reviews, meta-analyses, and randomized controlled trials published from 2015-2023. Outcomes of interest included quality of life (QOL), patient satisfaction, physical and psychological symptoms, survival, and caregiver burden. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations.
The literature search identified 52 relevant studies to inform the evidence base for this guideline.
Evidence-based recommendations address the integration of palliative care in oncology. Oncology clinicians should refer patients with advanced solid tumors and hematologic malignancies to specialized interdisciplinary palliative care teams that provide outpatient and inpatient care beginning early in the course of the disease, alongside active treatment of their cancer. For patients with cancer with unaddressed physical, psychosocial, or spiritual distress, cancer care programs should provide dedicated specialist palliative care services complementing existing or emerging supportive care interventions. Oncology clinicians from across the interdisciplinary cancer care team may refer the caregivers (eg, family, chosen family, and friends) of patients with cancer to palliative care teams for additional support. The Expert Panel suggests early palliative care involvement, especially for patients with uncontrolled symptoms and QOL concerns. Clinicians caring for patients with solid tumors on phase I cancer trials may also refer them to specialist palliative care.Additional information is available at www.asco.org/supportive-care-guidelines.
为肿瘤临床医生、患者、非专业护理人员和姑息治疗临床医生提供循证指导,以更新 2016 年 ASCO 关于将姑息治疗纳入所有癌症患者标准肿瘤治疗的指南。
ASCO 召集了一个由医学、放射、血液肿瘤学、肿瘤护理、姑息治疗、社会工作、伦理、倡导和心理肿瘤学专家组成的专家小组。该小组进行了文献检索,包括 2015 年至 2023 年发表的系统评价、荟萃分析和随机对照试验。感兴趣的结果包括生活质量(QOL)、患者满意度、身体和心理症状、生存和护理人员负担。专家小组成员使用现有证据和非正式共识制定了循证指南建议。
文献检索确定了 52 项相关研究,为该指南的循证基础提供了信息。
循证建议涉及姑息治疗在肿瘤学中的整合。肿瘤临床医生应将晚期实体瘤和血液恶性肿瘤患者转介给专门的多学科姑息治疗团队,该团队在疾病早期开始提供门诊和住院治疗,同时对癌症进行积极治疗。对于癌症患者存在未得到解决的身体、心理社会或精神困扰的患者,癌症护理计划应提供专门的姑息治疗服务,补充现有的或新出现的支持性护理干预措施。来自跨学科癌症护理团队的肿瘤临床医生可以将癌症患者的护理人员(如家庭、选择的家庭和朋友)转介给姑息治疗团队以获得额外支持。专家组建议尽早进行姑息治疗,特别是对症状未得到控制和 QOL 存在问题的患者。在 I 期癌症试验中接受治疗的实体瘤患者的临床医生也可以将他们转介给专业姑息治疗团队。更多信息请访问 www.asco.org/supportive-care-guidelines。