Zhou Zhiguo, Xiong Wei, Li Li, Li Feng
Department of Orthopaedics, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan Department of Orthopaedics Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Medicine (Baltimore). 2017 Jun;96(22):e7056. doi: 10.1097/MD.0000000000007056.
Adjacent segmental degeneration (ASD) is a major issue after pedicular fixation. This study examined the degeneration of the adjacent levels due to the insertion of the Wallis interspinous stabilization system compared with discectomy, using magnetic resonance imaging (MRI).Thirty-eight patients diagnosed with lumbar degeneration disorders at L4-L5 were reviewed: 19 patients underwent discectomy and Wallis system implantation (group A), and 19 patients underwent discectomy (group B). The Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) were assessed preoperatively and postoperatively. ASD was evaluated by MRI.There was no difference in the preoperative ODI scores between the 2 groups (non-normal distribution, median, 50 (40, 50) vs 50 (50, 50), P = .331), but the postoperative ODI scores were different (non-normal distribution, median, 0 (0, 32) vs 20 (20, 30), P < .005). Similar results were observed for VAS. In group A, ASD occurred in 4 patients (21.1%) in the disc and 8 (42.1%) in the facet joint at L3/4, and in 4 (21.1%) in the disc and 5 (26.3%) in the facet joint at L5/S1. In Group B, ASD occurred in 3 patients (15.8%) in the disc at L3/4, and in 4 (21.1%) in the disc at L5/S1. In general, there was no difference between the 2 groups (P > .05), except at L3/4 (P = .015).ASD of the facet joint in the cranial segment occurred after Wallis system implantation, suggesting that the Wallis system cannot prevent ASD of the facet joint, but could have some other benefits for the discs.
相邻节段退变(ASD)是椎弓根固定术后的一个主要问题。本研究采用磁共振成像(MRI),对比了Wallis棘突间稳定系统植入与椎间盘切除术后相邻节段的退变情况。回顾性分析了38例诊断为L4-L5节段腰椎退变疾病的患者:19例患者接受了椎间盘切除术并植入Wallis系统(A组),19例患者仅接受了椎间盘切除术(B组)。术前及术后采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)进行评估。通过MRI评估ASD。两组术前ODI评分无差异(非正态分布,中位数,50(40,50)对50(50,50),P = 0.331),但术后ODI评分不同(非正态分布,中位数,0(0,32)对20(20,30),P < 0.005)。VAS也观察到类似结果。在A组中,L3/4节段椎间盘发生ASD的有4例(21.1%),小关节发生ASD的有8例(42.1%);L5/S1节段椎间盘发生ASD的有4例(21.1%),小关节发生ASD的有5例(26.3%)。在B组中,L3/4节段椎间盘发生ASD的有3例(15.8%),L5/S1节段椎间盘发生ASD的有4例(21.1%)。总体而言,两组之间无差异(P > 0.05),但L3/4节段除外(P = 0.015)。Wallis系统植入后发生了上位节段小关节的ASD,提示Wallis系统不能预防小关节的ASD,但可能对椎间盘有其他益处。