Del Pezzo M, Gobbo M L, Miloso M, Gulletta E
Dipartimento di Biologia e Patologia Cellulare e Molecolare, II Facoltà di Medicina, Università degli Studi, Napoli.
G Batteriol Virol Immunol. 1988 Jan-Dec;81(1-12):25-31.
The Authors have evaluated, by DNA-probe hybridization, the presence of CMV in the cellular fractions of different body fluids from immunocompromised patients. This specific methodology appear to be rapid to perform, adaptable to different clinical samples and sensitive. Even in absence of a supporting evaluation of specific antibodies, direct detection of virus, by DNA-probe, seems to be the most efficient and rapid approach to confirm the diagnosis either of active phase or reactivating of CMV infection.
作者通过DNA探针杂交技术，评估了免疫功能低下患者不同体液细胞组分中巨细胞病毒（CMV）的存在情况。这种特定方法执行起来似乎很快，适用于不同临床样本且灵敏度高。即使没有对特异性抗体进行辅助评估，通过DNA探针直接检测病毒，似乎也是确认CMV感染急性期或再激活期诊断的最有效、最快速的方法。
