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VMAT 交付系统的委托和质量保证:使用实时 EPID 成像的高效时间分辨系统。

Commissioning and quality assurance for VMAT delivery systems: An efficient time-resolved system using real-time EPID imaging.

机构信息

Central Coast Cancer Centre, Gosford Hospital, Gosford, NSW, 2250, Australia.

School of Mathematical and Physical Sciences, University of Newcastle, Newcastle, NSW, 2308, Australia.

出版信息

Med Phys. 2017 Aug;44(8):3909-3922. doi: 10.1002/mp.12387. Epub 2017 Jul 10.

Abstract

PURPOSE

An ideal commissioning and quality assurance (QA) program for Volumetric Modulated Arc Therapy (VMAT) delivery systems should assess the performance of each individual dynamic component as a function of gantry angle. Procedures within such a program should also be time-efficient, independent of the delivery system and be sensitive to all types of errors. The purpose of this work is to develop a system for automated time-resolved commissioning and QA of VMAT control systems which meets these criteria.

METHODS

The procedures developed within this work rely solely on images obtained, using an electronic portal imaging device (EPID) without the presence of a phantom. During the delivery of specially designed VMAT test plans, EPID frames were acquired at 9.5 Hz, using a frame grabber. The set of test plans was developed to individually assess the performance of the dose delivery and multileaf collimator (MLC) control systems under varying levels of delivery complexities. An in-house software tool was developed to automatically extract features from the EPID images and evaluate the following characteristics as a function of gantry angle: dose delivery accuracy, dose rate constancy, beam profile constancy, gantry speed constancy, dynamic MLC positioning accuracy, MLC speed and acceleration constancy, and synchronization between gantry angle, MLC positioning and dose rate. Machine log files were also acquired during each delivery and subsequently compared to information extracted from EPID image frames.

RESULTS

The largest difference between measured and planned dose at any gantry angle was 0.8% which correlated with rapid changes in dose rate and gantry speed. For all other test plans, the dose delivered was within 0.25% of the planned dose for all gantry angles. Profile constancy was not found to vary with gantry angle for tests where gantry speed and dose rate were constant, however, for tests with varying dose rate and gantry speed, segments with lower dose rate and higher gantry speed exhibited less profile stability. MLC positional accuracy was not observed to be dependent on the degree of interdigitation. MLC speed was measured for each individual leaf and slower leaf speeds were shown to be compensated for by lower dose rates. The test procedures were found to be sensitive to 1 mm systematic MLC errors, 1 mm random MLC errors, 0.4 mm MLC gap errors and synchronization errors between the MLC, dose rate and gantry angle controls systems of 1°. In general, parameters measured by both EPID and log files agreed with the plan, however, a greater average departure from the plan was evidenced by the EPID measurements.

CONCLUSION

QA test plans and analysis methods have been developed to assess the performance of each dynamic component of VMAT deliveries individually and as a function of gantry angle. This methodology relies solely on time-resolved EPID imaging without the presence of a phantom and has been shown to be sensitive to a range of delivery errors. The procedures developed in this work are both comprehensive and time-efficient and can be used for streamlined commissioning and QA of VMAT delivery systems.

摘要

目的

用于容积调强弧形治疗(VMAT)交付系统的理想调试和质量保证(QA)程序应该评估每个单独动态组件的性能,作为旋转角度的函数。该程序中的程序也应该是高效的,独立于交付系统,并对所有类型的错误敏感。这项工作的目的是开发一种用于自动时间分辨的 VMAT 控制系统调试和 QA 的系统,该系统满足这些标准。

方法

本工作中开发的程序仅依赖于使用电子射野影像装置(EPID)获得的图像,而无需使用体模。在专门设计的 VMAT 测试计划的交付过程中,使用帧抓取器以 9.5 Hz 的频率获取 EPID 帧。该组测试计划的开发目的是单独评估在不同交付复杂程度下剂量输送和多叶准直器(MLC)控制系统的性能。开发了一个内部软件工具,从 EPID 图像中自动提取特征,并根据旋转角度评估以下特性:剂量输送精度、剂量率常数、射束轮廓常数、旋转架速度常数、动态 MLC 定位精度、MLC 速度和加速度常数以及旋转架角度、MLC 定位和剂量率之间的同步。在每次交付期间还获取了机器日志文件,并随后将其与从 EPID 图像帧中提取的信息进行比较。

结果

在任何旋转角度下,测量剂量与计划剂量的最大差异为 0.8%,这与剂量率和旋转架速度的快速变化相关。对于所有其他测试计划,对于所有旋转角度,输送的剂量都在计划剂量的 0.25%以内。对于旋转架速度和剂量率恒定的测试,未发现轮廓常数随旋转架角度变化,但对于剂量率和旋转架速度变化的测试,剂量率较低且旋转架速度较高的部分显示出较低的轮廓稳定性。未观察到 MLC 位置精度取决于互锁程度。为每个单独的叶片测量了 MLC 速度,并且较慢的叶片速度通过较低的剂量率来补偿。测试程序对 1 毫米系统 MLC 误差、1 毫米随机 MLC 误差、0.4 毫米 MLC 间隙误差和 MLC、剂量率和旋转架角度控制系统之间的 1°同步误差敏感。一般来说,EPID 和日志文件测量的参数与计划相符,但是 EPID 测量显示出更大的平均偏离计划。

结论

已经开发了 QA 测试计划和分析方法,用于单独评估 VMAT 输送的每个动态组件的性能,并作为旋转角度的函数。该方法仅依赖于具有时间分辨能力的 EPID 成像,而无需使用体模,并且已经证明对一系列输送误差敏感。本工作中开发的程序既全面又高效,可以用于简化 VMAT 输送系统的调试和 QA。

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