Yamaguchi Daisuke, Sakata Yasuhisa, Yoshida Hisako, Furukawa Naoko E, Tsuruoka Nanae, Higuchi Toru, Watanabe Akira, Shimoda Ryo, Tsunada Seiji, Iwakiri Ryuichi, Fujimoto Kazuma
Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Saga, Japan.
Digestion. 2017;95(4):319-326. doi: 10.1159/000477439. Epub 2017 Jun 1.
BACKGROUND/AIMS: In this study, investigations were carried out to ascertain whether soft coagulation hemostasis for non-variceal upper gastrointestinal bleeding (UGIB) has ever been performed in a time-dependent manner.
Medical records of 502 patients who had undergone emergency endoscopic hemostasis for non-variceal UGIB from 2003 to 2014 were checked and the modalities were used to achieve hemostasis compared between the first period from 2003 to 2008 (197 patients) and the second period from 2009 to 2014 (305 patients).
Endoscopic hemostasis was successfully achieved in 96.0% of study patients. Peptic ulcers were the main cause of bleeding (89.4%). Endoscopic hemostasis was performed by soft coagulation significantly more frequently during the second (71.1%) than the first period (11.7%; p < 0.001). Endoscopic hemostasis was mainly achieved by trainees during the second period (76.1%); these trainees comprised a significantly greater proportion of endoscopists than during the first period (56.3%; p < 0.001). Endoscopic-related complications did not differ between the 2 periods. The only risk factor for rebleeding after hemostasis was Helicobacter pylori infection; the use of soft coagulation and the fact that endoscopists were just trainees were not risk factors.
Our findings suggest that using soft coagulation to achieve endoscopic hemostasis for non-variceal UGIB is safe and effective, even when it is performed by trainees.
背景/目的:本研究旨在确定非静脉曲张性上消化道出血(UGIB)的软凝止血是否曾按时间依赖性方式进行。
检查了2003年至2014年期间502例因非静脉曲张性UGIB接受急诊内镜止血的患者的病历,并比较了2003年至2008年第一阶段(197例患者)和2009年至2014年第二阶段(305例患者)实现止血所使用的方式。
96.0%的研究患者成功实现内镜止血。消化性溃疡是出血的主要原因(89.4%)。在第二阶段(71.1%),通过软凝进行内镜止血的频率明显高于第一阶段(11.7%;p<0.001)。在第二阶段,内镜止血主要由实习医生完成(76.1%);这些实习医生在内镜医生中所占比例明显高于第一阶段(56.3%;p<0.001)。两个阶段的内镜相关并发症无差异。止血后再出血的唯一危险因素是幽门螺杆菌感染;使用软凝以及内镜医生是实习医生这一事实不是危险因素。
我们的研究结果表明,即使由实习医生进行,使用软凝实现非静脉曲张性UGIB的内镜止血也是安全有效的。