革兰氏阴性菌中的β-内酰胺耐药机制。
Beta-lactam resistance mechanisms in gram-negative bacteria.
作者信息
Cole S T, Nicolas M H
机构信息
Unité des Applications du Génie Génétique, Institute Pasteur, Paris, France.
出版信息
Microbiol Sci. 1986 Nov;3(11):334-9.
PMID:2856616
Abstract
Beta-lactam antibiotics are commonly used to treat a variety of bacterial infections. Gram-negative bacteria have evolved several resistance mechanisms including altered permeability and beta-lactamase production. New trends in resistance are emerging amongst clinical isolates which may reflect the choice of beta-lactam employed.
摘要
β-内酰胺类抗生素常用于治疗多种细菌感染。革兰氏阴性菌已进化出多种耐药机制，包括通透性改变和β-内酰胺酶产生。临床分离株中出现了新的耐药趋势，这可能反映了所使用的β-内酰胺类药物的选择。
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