恰当的时间，恰当的地点：发育基因表达的时间调控
Right time, right place: the temporal regulation of developmental gene expression.
作者信息
Praggastis Sophia A, Thummel Carl S
机构信息
Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA.
出版信息
Genes Dev. 2017 May 1;31(9):847-848. doi: 10.1101/gad.301002.117.
Abstract
Many studies have focused on defining the critical transcription factors that specify tissue morphogenesis and differentiation. Our understanding of how these spatial regulators are deployed in the proper temporal order, however, has remained less clear. In this issue of , Uyehara and colleagues (pp. 862-875) provide new insights into the mechanisms by which temporal and spatial regulators are coordinated to control wing development during metamorphosis.
摘要
许多研究都集中在确定那些决定组织形态发生和分化的关键转录因子上。然而，我们对于这些空间调节因子如何按照正确的时间顺序发挥作用的理解，仍不够清晰。在本期杂志中，上原及其同事（第862 - 875页）对在变态发育过程中，时间和空间调节因子如何协同控制翅膀发育的机制提供了新的见解。
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