Sakurai Yasuhisa, Nakashima Yoshifumi
Department of Neurology, Mitsui Memorial Hospital, Japan.
Department of Psychiatry, Mitsui Memorial Hospital, Japan.
Intern Med. 2017;56(11):1421-1424. doi: 10.2169/internalmedicine.56.7005. Epub 2017 Jun 1.
We herein report a 65-year-old man demonstrating dementia with Lewy bodies who first presented with Bálint's syndrome. Two years later, a mild cognitive impairment was noted. From three years after onset, he developed progressive parkinsonism, visual hallucination, and autonomic dysfunction, in line with the deterioration of the cognitive function. Single photon emission computed tomography with a Tc-ethylcysteinate dimer performed two years after onset revealed hypoperfusion in the restricted area of the bilateral superior parietal lobule, which extended to the lateral occipital cortices within two years. It is suggested that the pathological process can extend from the parietal to occipital lobes.
我们在此报告一名65岁患有路易体痴呆的男性,其最初表现为巴林特综合征。两年后,出现轻度认知障碍。发病三年后,随着认知功能的恶化,他出现了进行性帕金森症、视幻觉和自主神经功能障碍。发病两年后进行的锝-乙半胱氨酸二聚体单光子发射计算机断层扫描显示双侧顶上小叶受限区域灌注不足,两年内扩展至枕外侧皮质。提示病理过程可从顶叶扩展至枕叶。