Strano A, Novo S, Pinto A, Fasulo S, Alaimo G
Institute of Clinical Medicine, University of Palermo, Italy.
J Hypertens Suppl. 1985 Dec;3(3):S351-3.
Hypertension is associated with increased total peripheral vascular resistance. Calf blood flow and vascular resistance in two groups of hypertensives of different age has been evaluated: 85 middle-aged hypertensives (MH) and 25 elderly hypertensives (EH), and in two groups of 20 normotensive control subjects of similar age. Calf blood flow at rest (RF) and after ischaemia (PF) was determined by strain-gauge plethysmography. Basal (BVR) and minimal (MVR) vascular resistance were obtained by the mean blood pressure (MBP):RF and MBP:PF ratio. Blood flow at rest was reduced only in EH, while PF was significantly lower in MH and in EH in comparison with the respective controls. In parallel, BVR and MVR were higher in MH and in EH compared with controls. The increase of BVR and of MVR was more evident in EH. These results suggest that in EH there is an impairment of the calf maximal vasodilatation capacity, probably due to the long duration of hypertension.
高血压与总外周血管阻力增加有关。对两组不同年龄的高血压患者的小腿血流和血管阻力进行了评估：85名中年高血压患者（MH）和25名老年高血压患者（EH），以及两组各20名年龄相仿的血压正常对照者。通过应变片体积描记法测定静息时（RF）和缺血后（PF）的小腿血流。基础血管阻力（BVR）和最小血管阻力（MVR）通过平均血压（MBP）：RF和MBP：PF比值获得。仅EH组静息血流减少，而与各自对照组相比，MH组和EH组的PF显著降低。同时，与对照组相比，MH组和EH组的BVR和MVR更高。EH组BVR和MVR的增加更为明显。这些结果表明，EH组存在小腿最大血管舒张能力受损，可能是由于高血压病程较长所致。
