Ropson Ira J, Brown Ew C, Powers Dennis A
Department of Biology, Johns Hopkins University, Baltimore, MD, 21218.
Evolution. 1990 Feb;44(1):16-26. doi: 10.1111/j.1558-5646.1990.tb04276.x.
Geographic variation in the gene frequencies corresponding to 15 polymorphic enzymes were studied in the common killifish Fundulus heteroclitus. Aat-A, Est-B, Fum-A, H6pdh-A, Mpi-A and Pgm-B showed clinal variation in allelic frequencies along the Atlantic coast of North America, while Aat-B, Ap-A, and the EST-C phenotypes did not. The clinal allelic variation of six previously examined loci (Ldh-B, Mdh-A, Gpi-B, Idh-A, Pgm-A, and 6-Pgdh-A) was extended to locations farther north. Gene diversity was lowest in the cold waters of northern latitudes and highest in the warmer waters of southern latitudes. The variety of clinal shapes and widths suggests that selection has affected the allelic distributions for at least some of these loci. This hypothesis is discussed with regard to the range contractions and extensions caused by the glacial advances and retreats during the Pleistocene.
对常见鳉鱼（Fundulus heteroclitus）中与15种多态酶相对应的基因频率的地理变异进行了研究。Aat-A、Est-B、Fum-A、H6pdh-A、Mpi-A和Pgm-B在北美洲大西洋沿岸的等位基因频率呈现渐变变异，而Aat-B、Ap-A和EST-C表型则没有。六个先前检测位点（Ldh-B、Mdh-A、Gpi-B、Idh-A、Pgm-A和6-Pgdh-A）的渐变等位基因变异扩展到了更北的位置。基因多样性在北纬的冷水区域最低，在南纬较温暖的水域最高。渐变形状和宽度的多样性表明，选择至少对其中一些位点的等位基因分布产生了影响。关于更新世期间冰川进退引起的分布范围收缩和扩展，对这一假设进行了讨论。
