Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
作者信息
Kharas Michael G, Janes Matthew R, Scarfone Vanessa M, Lilly Michael B, Knight Zachary A, Shokat Kevan M, Fruman David A
出版信息
J Clin Invest. 2017 Jun 1;127(6):2438. doi: 10.1172/JCI95182.
Abstract
摘要
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