Pediatric Radiology, Faculty of Medicine, Erciyes University, 38039 Kayseri, Turkey.
Biomedical Imaging Research Center, Erciyes University, 38039 Kayseri, Turkey.
Diagn Interv Imaging. 2017 Oct;98(10):707-714. doi: 10.1016/j.diii.2017.05.004. Epub 2017 May 29.
To prospectively compare the diagnostic capabilities of quantitative susceptibility mapping (QSM) with those of phase images of susceptibility-weighted imaging (SWI) in the detection and differentiation of intracranial calcification and hemorrhage in pediatric patients.
Sixteen pediatric patients (9 girls, 7 boys) with a mean age of 9.4±6.3 (SD) years (range, 6 days-15 years) were included. Fifty-nine calcifications and 31 hemorrhages were detected. Sensitivities and specificities of the two magnetic resonance (MR) imaging techniques were calculated and compared using McNemar test.
QSM had a sensitivity of 84.7% and specificity of 100% for the detection of calcification. SWI phase images had a sensitivity of 49.1% and specificity of 100%. For the detection of hemorrhage, QSM had a sensitivity of 90.3% and a specificity of 98.3% whereas SWI phase images yielded a sensitivity of 64.5% and specificity of 96.6%. Overall, QSM displayed significantly better sensitivity than SWI phase images in identification of calcification and hemorrhage (P<0.05).
QSM is more reliable than SWI phase images in the identification of intracranial calcification and hemorrhage in pediatric patients using MR imaging.
前瞻性比较定量磁化率映射（QSM）与磁敏感加权成像（SWI）相位图在检测和区分儿科患者颅内钙化和出血中的诊断能力。
纳入 16 例平均年龄 9.4±6.3（SD）岁（范围，6 天-15 岁）的儿科患者（9 女，7 男）。共检出 59 个钙化灶和 31 个出血灶。采用 McNemar 检验比较两种磁共振成像（MR）技术的灵敏度和特异性。
QSM 检测钙化的灵敏度为 84.7%，特异性为 100%。SWI 相位图的灵敏度为 49.1%，特异性为 100%。对于出血的检测，QSM 的灵敏度为 90.3%，特异性为 98.3%，而 SWI 相位图的灵敏度为 64.5%，特异性为 96.6%。总体而言，QSM 在识别钙化和出血方面的灵敏度明显优于 SWI 相位图（P<0.05）。
与 SWI 相位图相比，QSM 更可靠地识别儿科患者颅内钙化和出血。
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