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本文引用的文献

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Cancer statistics, 2016.癌症统计数据,2016 年。
CA Cancer J Clin. 2016 Jan-Feb;66(1):7-30. doi: 10.3322/caac.21332. Epub 2016 Jan 7.
2
Colorectal cancer: Metastases to a single organ.结直肠癌:转移至单一器官。
World J Gastroenterol. 2015 Nov 7;21(41):11767-76. doi: 10.3748/wjg.v21.i41.11767.
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Mechanisms of disseminated cancer cell dormancy: an awakening field.播散性癌细胞休眠的机制:一个觉醒的领域。
Nat Rev Cancer. 2014 Sep;14(9):611-22. doi: 10.1038/nrc3793. Epub 2014 Aug 14.
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Advanced colorectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up.晚期结直肠癌:欧洲肿瘤内科学会关于诊断、治疗及随访的临床建议
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Systemic spread is an early step in breast cancer.全身扩散是乳腺癌的早期阶段。
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6
Resection of pulmonary metastases from colorectal carcinoma.结直肠癌肺转移灶切除术
Eur J Surg Oncol. 2007 Dec;33 Suppl 2:S59-63. doi: 10.1016/j.ejso.2007.09.018. Epub 2007 Nov 26.
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Colorectal cancer surveillance: 2005 update of an American Society of Clinical Oncology practice guideline.结直肠癌监测:美国临床肿瘤学会实践指南2005年更新版
J Clin Oncol. 2005 Nov 20;23(33):8512-9. doi: 10.1200/JCO.2005.04.0063. Epub 2005 Oct 31.
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Colorectal adenomas: a prototype for the use of surrogate end points in the development of cancer prevention drugs.
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The process of metastasisation for breast cancer.乳腺癌的转移过程。
Eur J Cancer. 2003 Aug;39(12):1794-806. doi: 10.1016/s0959-8049(03)00422-2.
10
Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992.未知原发肿瘤的流行病学;1984 - 1992年荷兰东南部1285例患者的发病率及基于人群的生存率
Eur J Cancer. 2002 Feb;38(3):409-13. doi: 10.1016/s0959-8049(01)00378-1.

原发性乙状结肠癌10多年后出现的晚期肺转移。

Late onset pulmonary metastasis more than 10 years after primary sigmoid carcinoma.

作者信息

Daniels Anne M, Vogelaar Jeroen F J

机构信息

Anne M Daniels, Jeroen F J Vogelaar, Department of Surgery, VieCuri Medical Centre, 5912 BL Venlo, The Netherlands.

出版信息

World J Gastrointest Pathophysiol. 2017 May 15;8(2):96-99. doi: 10.4291/wjgp.v8.i2.96.

DOI:10.4291/wjgp.v8.i2.96
PMID:28573073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5437508/
Abstract

According to current guidelines, follow-up of patients with colorectal cancer is ended after five years. Also, chest X-ray is not part of standard investigation during follow-up. We describe a case of a 74-year-old patient, more than ten years after a sigmoid resection because of carcinoma of the sigmoid. No recurrence was detected during intensive follow-up. However, ten years after resection of the sigmoid adenocarcinoma, complaints of coughing induced further examination with as result the detection of a solitary metastasis in the left lung of the patient. Within half-a-year after metastasectomy of the lung metastasis, she presented herself with thoracic pain and dyspnea resulting in discovering diffuse metastasis on pulmonary, pleural, costal and muscular level. Five year follow-up of colorectal carcinoma without chest X-ray can be questioned to be efficient. The growing knowledge of tumor biology might in future adjust the duration and frequency of diagnostic follow-up to prevent (late) recurrence in patients with colorectal carcinoma.

摘要

根据现行指南,结直肠癌患者的随访在五年后结束。此外,胸部X光检查并非随访期间标准检查的一部分。我们描述了一例74岁患者的病例,该患者因乙状结肠癌接受乙状结肠切除术后十多年。在密集随访期间未检测到复发。然而,在乙状结肠腺癌切除术后十年,咳嗽症状促使进一步检查,结果在患者左肺发现了一个孤立转移灶。在肺转移灶切除术后半年内,她出现胸痛和呼吸困难,结果发现肺部、胸膜、肋骨和肌肉层面有弥漫性转移。不进行胸部X光检查的结直肠癌五年随访是否有效值得质疑。肿瘤生物学知识的不断增长可能会在未来调整诊断随访的时长和频率,以预防结直肠癌患者(晚期)复发。