Duan Fang, Liao Jingyu, Lin Liping, Liu Xiuping, Wu Kaili
Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Biomed Res Int. 2017;2017:8920350. doi: 10.1155/2017/8920350. Epub 2017 May 10.
To investigate the prevalence of laboratory critical results (CRs) and associated risk factors in patients with eye diseases in a tertiary eye hospital.
Blood samples were collected from both inpatients and outpatients at Zhongshan Ophthalmic Center, Guangzhou, China, from June 1, 2012, to May 31, 2014, and samples were sent to the hospital's clinical laboratory for blood routine, biochemistry, and blood coagulation tests. Laboratory CRs for blood glucose, sodium, potassium, white blood cell count, platelet count, prothrombin time, fibrinogen, international normalized ratio, and activated partial thromboplastin time were included in the current analysis.
A total of 60403 subjects were enrolled in the current analysis. CRs were identified in 339 tests from 336 patients with a prevalence of 5.7‰. Age was positively associated with the presence of CRs. Compared to patients with lens diseases, patients with strabismus, oculoplastics, and ocular trauma were less likely to have CRs ( < 0.05), while patients with tumors were more likely to have CRs ( < 0.001).
The prevalence of CRs in eye patients is low but calls for medication attention. It is important for medical personnel, especially ophthalmologists, to increase awareness of the importance, as well as the prevalence and risk factors of CRs.
调查三级眼科医院眼科疾病患者实验室危急值(CRs)的发生率及相关危险因素。
于2012年6月1日至2014年5月31日在中国广州中山眼科中心收集住院患者和门诊患者的血样,并将样本送至医院临床实验室进行血常规、生化和凝血检测。本次分析纳入血糖、钠、钾、白细胞计数、血小板计数、凝血酶原时间、纤维蛋白原、国际标准化比值和活化部分凝血活酶时间的实验室危急值。
本分析共纳入60403名受试者。在336例患者的339次检测中发现危急值,发生率为5.7‰。年龄与危急值的存在呈正相关。与晶状体疾病患者相比,斜视、眼整形和眼外伤患者发生危急值的可能性较小(<0.05),而肿瘤患者发生危急值的可能性较大(<0.001)。
眼科患者危急值的发生率较低,但需要引起药物治疗方面的关注。医务人员,尤其是眼科医生,提高对危急值的重要性、发生率及危险因素的认识很重要。