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Structurxplor:一个用于探索 RNA 二级结构结构特征的平台。

Structurexplor: a platform for the exploration of structural features of RNA secondary structures.

机构信息

Department of Computer Science, Faculty of Science, Université de Sherbrooke, Sherbrooke, QC, J1K 2R1 Canada.

RNA Group, Department of Biochemistry, Faculty of Medicine and Health Sciences, Applied Cancer Research Pavilion, Université de Sherbrooke, Sherbrooke, QC, J1K 2R1, Canada.

出版信息

Bioinformatics. 2017 Oct 1;33(19):3117-3120. doi: 10.1093/bioinformatics/btx323.

Abstract

SUMMARY

Discovering function-related structural features, such as the cloverleaf shape of transfer RNA secondary structures, is essential to understand RNA function. With this aim, we have developed a platform, named Structurexplor, to facilitate the exploration of structural features in populations of RNA secondary structures. It has been designed and developed to help biologists interactively search for, evaluate and select interesting structural features that can potentially explain RNA functions.

AVAILABILITY AND IMPLEMENTATION

Structurxplor is a web application available at http://structurexplor.dinf.usherbrooke.ca. The source code can be found at http://jpsglouzon.github.io/structurexplor/.

CONTACT

shengrui.wang@usherbrooke.ca.

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

摘要

发现与功能相关的结构特征,如转移 RNA 二级结构的三叶草形状,对于理解 RNA 功能至关重要。为此,我们开发了一个名为 Structurexplor 的平台,以促进对 RNA 二级结构群体中结构特征的探索。它旨在帮助生物学家交互式地搜索、评估和选择可能解释 RNA 功能的有趣结构特征。

可用性和实现

Structurxplor 是一个网络应用程序,可在 http://structurexplor.dinf.usherbrooke.ca 上获得。源代码可在 http://jpsglouzon.github.io/structurexplor/ 找到。

联系人

shengrui.wang@usherbrooke.ca

补充信息

补充数据可在“Bioinformatics”在线获得。

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