Santiago Esteban, Yang Yelin, Conlon Ronan, Compan Javiera, Baig Kashif, Ziai Setareh
University of Ottawa Eye Institute, Ottawa, Ont.
University of Ottawa Eye Institute, Ottawa, Ont..
Can J Ophthalmol. 2017 Jun;52(3):308-312. doi: 10.1016/j.jcjo.2016.11.003. Epub 2016 Dec 23.
The aim of this study was to evaluate the outcomes of paste-pinch-cut conjunctivoplasty and cautery conjunctivoplasty for the treatment of symptomatic conjunctivochalasis.
This was a prospective cohort study.
Sixteen patients (32 eyes) with bilateral conjunctivochalasis that was symptomatic after medical therapy were enrolled in the study.
This was a single-centre, contralateral eye, prospective study. Paste-pinch-cut conjunctivoplasty was performed in the left eye, and thermal cautery conjunctivoplasty was performed in the right eye. The outcomes of each procedure were compared preoperatively and at the 1-month follow-up by using the Canadian Dry Eye Assessment (CDEA) scoring system, standard conjunctivochalasis grading, and corneal staining. Intraoperative discomfort and immediate postoperative discomfort were assessed by using a 10-point scale.
The mean age of patients was 72.4 ± 8.67 years. Conjunctival redundancy was absent in 14 of 16 patients postoperatively. The mean CDEA score improved after both procedures (7.1 ± 2.8 preoperatively versus 4.5 ± 0.78 at the 1-month follow-up for cautery conjunctivoplasty, 7.4 ± 2.5 versus 4.9 ± 3.1 for paste-pinch-cut conjunctivoplasty). This improvement was statistically significant in the cautery conjunctivoplasty group (p = 0.012). Mean intraoperative discomfort was 2.6 ± 2.1 with the use of paste-pinch-cut conjunctivoplasty and 3.5 ± 3.2 with the use of cautery conjunctivoplasty; however, the difference was not statistically significant. No intraoperative or postoperative complications were observed with either technique.
Paste-pinch-cut and thermal cautery conjunctivoplasty are both safe and effective surgical treatments for the repair of conjunctivochalasis, with patients reporting greater improvement in symptoms after the cautery technique.
本研究旨在评估粘贴-捏切结膜成形术和烧灼结膜成形术治疗有症状结膜松弛症的效果。
这是一项前瞻性队列研究。
16例(32只眼)双侧结膜松弛症患者,经药物治疗后仍有症状,纳入本研究。
这是一项单中心、对侧眼的前瞻性研究。左眼行粘贴-捏切结膜成形术,右眼行热烧灼结膜成形术。术前及术后1个月随访时,采用加拿大干眼评估(CDEA)评分系统、标准结膜松弛分级和角膜染色比较每种手术的效果。术中不适和术后即刻不适采用10分制进行评估。
患者的平均年龄为72.4±8.67岁。术后16例患者中有14例结膜冗余消失。两种手术后平均CDEA评分均有所改善(烧灼结膜成形术术前为7.1±2.8,术后1个月随访时为4.5±0.78;粘贴-捏切结膜成形术术前为7.4±2.5,术后1个月随访时为4.9±3.1)。烧灼结膜成形术组的这种改善具有统计学意义(p = 0.012)。粘贴-捏切结膜成形术的平均术中不适评分为2.6±2.1,烧灼结膜成形术为(3.5±3.2);然而,差异无统计学意义。两种技术均未观察到术中或术后并发症。
粘贴-捏切和热烧灼结膜成形术都是修复结膜松弛症安全有效的手术治疗方法,患者报告烧灼技术术后症状改善更明显。