• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

自体骨软骨移植

Osteochondral Autologous Transplantation.

作者信息

Sherman Seth L, Thyssen Emil, Nuelle Clayton W

机构信息

Department of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA; Missouri Orthopaedic Institute, 1100 Virginia Avenue, Columbia, MO 65212, USA.

School of Medicine, University of Missouri, One Hospital Drive, MA204, Columbia, MO 65212, USA.

出版信息

Clin Sports Med. 2017 Jul;36(3):489-500. doi: 10.1016/j.csm.2017.02.006. Epub 2017 Apr 26.

DOI:10.1016/j.csm.2017.02.006
PMID:28577708
Abstract

Osteochondral autologous transplantation (OAT) is a treatment strategy for small and medium sized focal articular cartilage defects in the knee. This article reviews the indications, surgical techniques, outcomes, and limitations of OAT for the management of symptomatic chondral and osteochondral lesions in the knee joint.

摘要

自体骨软骨移植(OAT)是治疗膝关节中小面积局灶性关节软骨缺损的一种治疗策略。本文综述了OAT治疗膝关节有症状软骨和骨软骨损伤的适应症、手术技术、疗效及局限性。

相似文献

1
Osteochondral Autologous Transplantation.自体骨软骨移植
Clin Sports Med. 2017 Jul;36(3):489-500. doi: 10.1016/j.csm.2017.02.006. Epub 2017 Apr 26.
2
Good short- to medium-term results after osteochondral autograft transplantation (OAT) in middle-aged patients with focal, non-traumatic osteochondral lesions of the knee.中年患者膝关节局灶性、非创伤性骨软骨损伤行自体骨软骨移植(OAT)后,短期至中期效果良好。
Orthop Traumatol Surg Res. 2016 Nov;102(7):879-884. doi: 10.1016/j.otsr.2016.06.004. Epub 2016 Jul 19.
3
Isolated Osteochondral Autograft Versus Allograft Transplantation for the Treatment of Symptomatic Cartilage Lesions of the Knee: A Systematic Review and Meta-analysis.孤立性骨软骨自体移植与同种异体移植治疗膝关节症状性软骨病变:系统评价和荟萃分析。
Am J Sports Med. 2023 Mar;51(3):812-824. doi: 10.1177/03635465211053594. Epub 2022 Feb 9.
4
Allografts: Osteochondral, Shell, and Paste.同种异体移植物:骨软骨移植物、壳状移植物和膏状移植物。
Clin Sports Med. 2017 Jul;36(3):509-523. doi: 10.1016/j.csm.2017.02.007. Epub 2017 May 2.
5
Activity levels are higher after osteochondral autograft transfer mosaicplasty than after microfracture for articular cartilage defects of the knee: a retrospective comparative study.骨软骨马赛克移植成形术治疗膝关节软骨缺损后活动水平高于微骨折术:一项回顾性对比研究。
J Bone Joint Surg Am. 2012 Jun 6;94(11):971-8. doi: 10.2106/JBJS.K.00815.
6
Clinical Outcomes and Failure Rates of Osteochondral Allograft Transplantation in the Knee: A Systematic Review.关节镜下微骨折术与富血小板血浆注射治疗膝关节骨软骨损伤的随机对照研究
Am J Sports Med. 2018 Dec;46(14):3541-3549. doi: 10.1177/0363546517732531. Epub 2017 Oct 17.
7
Microfracture and Microfracture Plus.微骨折术及微骨折术联合其他治疗
Clin Sports Med. 2017 Jul;36(3):501-507. doi: 10.1016/j.csm.2017.02.012. Epub 2017 Apr 15.
8
Treatment of articular cartilage defects of the knee with autologous chondrocyte implantation.自体软骨细胞移植治疗膝关节软骨缺损
J Orthop Sports Phys Ther. 1998 Oct;28(4):241-51. doi: 10.2519/jospt.1998.28.4.241.
9
Osteochondral Autologous Transplantation Compared to Microfracture for Treating Osteochondral Defect: An Updated Meta-analysis of Randomized Controlled Trials.自体骨软骨移植与微骨折术治疗骨软骨缺损的比较:随机对照试验的最新荟萃分析
J Knee Surg. 2018 Apr;31(4):341-347. doi: 10.1055/s-0037-1603798. Epub 2017 Jun 23.
10
Management of Chondral Lesions of the Knee: Analysis of Trends and Short-Term Complications Using the National Surgical Quality Improvement Program Database.膝关节软骨病变的处理:利用国家手术质量改进计划数据库分析趋势和短期并发症。
Arthroscopy. 2019 Jan;35(1):138-146. doi: 10.1016/j.arthro.2018.07.049. Epub 2018 Nov 22.

引用本文的文献

1
Autologous Osteochondral Transplantation in Large Osteochondral Defects-A Follow-Up of 52 Patients After Knee Joint Resurfacing.大的骨软骨缺损的自体骨软骨移植——膝关节表面置换术后52例患者的随访
J Clin Med. 2025 Sep 1;14(17):6180. doi: 10.3390/jcm14176180.
2
Blockade of the Notch Pathway by Inhibition of Fucosylation Ameliorates Chondrocyte Inflammation and Extracellular Matrix Degradation.通过抑制岩藻糖基化阻断Notch信号通路可改善软骨细胞炎症和细胞外基质降解。
J Inflamm Res. 2025 Aug 18;18:11317-11334. doi: 10.2147/JIR.S520179. eCollection 2025.
3
The Inhibitory Effect of the Active Ingredients in the Bushen Huoxue Formula on the IL-17A Signaling Pathway and Its Alleviating Effect on Osteoarthritis.
补肾活血方有效成分对IL-17A信号通路的抑制作用及其对骨关节炎的缓解作用
J Inflamm Res. 2025 May 21;18:6505-6527. doi: 10.2147/JIR.S506716. eCollection 2025.
4
Immune-modulated adhesive hydrogel for enhancing osteochondral graft adhesion and cartilage repair.用于增强骨软骨移植物粘附和软骨修复的免疫调节粘性水凝胶
Bioact Mater. 2025 Mar 1;49:23-38. doi: 10.1016/j.bioactmat.2025.02.035. eCollection 2025 Jul.
5
Risk of Chondral Fracture During Implantation of Distal Femur Osteochondral Autograft Plugs: A Human Cadaveric Comparison of Four Different Donor Regions.股骨远端自体骨软骨移植栓植入过程中软骨骨折的风险:四个不同供体区域的人体尸体比较
Cartilage. 2024 Dec 20:19476035241308535. doi: 10.1177/19476035241308535.
6
Curcumin Alleviates Osteoarthritis Through the p38MAPK Pathway: Network Pharmacological Prediction and Experimental Confirmation.姜黄素通过p38丝裂原活化蛋白激酶途径减轻骨关节炎:网络药理学预测与实验验证
J Inflamm Res. 2024 Jul 26;17:5039-5056. doi: 10.2147/JIR.S459867. eCollection 2024.
7
Comparison of the Efficacy of Human Umbilical Cord-Derived and Bone Marrow Aspirate Concentrate Mesenchymal Stem Cells for Cartilage Repair Defects of the Knee via Arthroscopic Implementation on Scaffolds in a Retrospective Study.一项回顾性研究:通过关节镜在支架上实施,比较人脐带源间充质干细胞和骨髓抽吸浓缩物间充质干细胞对膝关节软骨修复缺损的疗效
J Pers Med. 2024 Feb 20;14(3):220. doi: 10.3390/jpm14030220.
8
3D printed osteochondral scaffolds: design strategies, present applications and future perspectives.3D打印骨软骨支架:设计策略、当前应用及未来展望
Front Bioeng Biotechnol. 2024 Feb 15;12:1339916. doi: 10.3389/fbioe.2024.1339916. eCollection 2024.
9
Clinical Potential of Cellular Material Sources in the Generation of iPSC-Based Products for the Regeneration of Articular Cartilage.细胞材料来源在基于 iPSC 的关节软骨再生产品中的临床潜力。
Int J Mol Sci. 2023 Sep 22;24(19):14408. doi: 10.3390/ijms241914408.
10
Surface morphology of osteochondral grafts harvested from femoral condyles with free-hand technique: a cadaveric study.徒手技术获取的股骨髁骨软骨移植物的表面形态:一项尸体研究
Eur J Orthop Surg Traumatol. 2024 Feb;34(2):853-862. doi: 10.1007/s00590-023-03731-7. Epub 2023 Sep 25.