Weber Walter P, Soysal Savas D, El-Tamer Mahmoud, Sacchini Virgilio, Knauer Michael, Tausch Christoph, Hauser Nik, Günthert Andreas, Harder Yves, Kappos Elisabeth A, Schwab Fabienne, Fitzal Florian, Dubsky Peter, Bjelic-Radisic Vesna, Reitsamer Roland, Koller Rupert, Heil Jörg, Hahn Markus, Blohmer Jens-Uwe, Hoffmann Jürgen, Solbach Christine, Heitmann Christoph, Gerber Bernd, Haug Martin, Kurzeder Christian
Breast Center, University Hospital Basel, Basel, Switzerland.
Memorial Sloan Kettering Cancer Center, New York, USA.
Breast Cancer Res Treat. 2017 Aug;165(1):139-149. doi: 10.1007/s10549-017-4314-5. Epub 2017 Jun 3.
PURPOSE: To obtain consensus recommendations for the standardization of oncoplastic breast conserving surgery (OPS) from an international panel of experts in breast surgery including delegates from the German, Austrian and Swiss societies of senology. METHODS: A total of 52 questions were addressed by electronic voting. The panel's recommendations were put into context with current evidence and the report was circled in an iterative open email process until consensus was obtained. RESULTS: The panelists considered OPS safe and effective for improving aesthetic outcomes and broadening the indication for breast conserving surgery (BCS) towards larger tumors. A slim majority believed that OPS reduces the rate of positive margins; however, there was consensus that OPS is associated with an increased risk of complications compared to conventional BCS. The panel strongly endorsed patient-reported outcomes measurement, and recommended selected scales of the Breast-Q™-Breast Conserving Therapy Module for that purpose. The Clough bi-level classification was recommended for standard use in clinical practice for indicating, planning and performing OPS, and the Hoffmann classification for surgical reports and billing purposes. Mastopexy and reduction mammoplasty were the only two recognized OPS procedure categories supported by a majority of the panel. Finally, the experts unanimously supported the statement that every OPS procedure should be tailored to each individual patient. CONCLUSIONS: When implemented into clinical practice, the panel recommendations may improve safety and effectiveness of OPS. The attendees agreed that there is a need for prospective multicenter studies to optimize patient selection and for standardized criteria to qualify and accredit OPS training centers.
目的:从包括德国、奥地利和瑞士乳腺病学会代表在内的国际乳腺外科专家小组中,获取关于肿瘤整形保乳手术(OPS)标准化的共识性建议。 方法:通过电子投票回答了总共52个问题。该小组的建议与当前证据相结合,并在一个反复的开放式电子邮件过程中进行完善,直至达成共识。 结果:小组成员认为OPS对于改善美学效果以及将保乳手术(BCS)的适应症扩大至更大肿瘤是安全有效的。微弱多数人认为OPS可降低切缘阳性率;然而,大家一致认为与传统BCS相比,OPS并发症风险增加。该小组强烈支持患者报告结局测量,并为此推荐了Breast-Q™保乳治疗模块的选定量表。推荐采用Clough双水平分类法在临床实践中标准用于OPS的指示、规划和实施,采用Hoffmann分类法用于手术报告和计费目的。乳房上提术和乳房缩小成形术是该小组多数人支持的仅有的两个公认的OPS手术类别。最后,专家们一致支持每个OPS手术都应根据每个患者的具体情况量身定制这一说法。 结论:当应用于临床实践时,该小组的建议可能会提高OPS的安全性和有效性。与会者一致认为,需要进行前瞻性多中心研究以优化患者选择,并需要标准化标准来对OPS培训中心进行资格认定和认证。
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