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牛蹄腐病的发病机制与治疗

Pathogenesis and Treatment of Bovine Foot Rot.

作者信息

Van Metre David C

机构信息

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 W. Drake Road, Fort Collins, CO 80523-1678, USA.

出版信息

Vet Clin North Am Food Anim Pract. 2017 Jul;33(2):183-194. doi: 10.1016/j.cvfa.2017.02.003.

DOI:10.1016/j.cvfa.2017.02.003
PMID:28579042
Abstract

Bovine foot rot (BFR) is an infectious disease of the interdigital skin and subcutaneous tissues of beef and dairy cattle that occurs under a variety of management and environmental settings. The anaerobic, gram-negative bacteria Fusobacterium necrophorum, Porphyromonas levii, and Prevotella intermedia are commonly isolated from lesions. A multitude of host, agent, and environmental factors contribute to the development of BFR. Initiation of systemic antimicrobial therapy early in the course of disease commonly leads to resolution. Delays in treatment may result in extension of infection into deeper bone, synovial structures, or ligamentous structures, and the prognosis for recovery is reduced.

摘要

牛蹄腐病(BFR)是肉牛和奶牛指间皮肤及皮下组织的一种传染病,在多种管理和环境条件下均可发生。坏死梭杆菌、利氏卟啉单胞菌和中间普雷沃菌等厌氧革兰氏阴性菌通常可从病变部位分离出来。许多宿主、病原体和环境因素都与牛蹄腐病的发生有关。在疾病早期开始全身抗菌治疗通常可使病情得到缓解。治疗延迟可能导致感染扩展至更深的骨骼、滑膜结构或韧带结构,从而降低恢复的预后。

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